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Ropivacaine

Generic Name
Ropivacaine
Brand Names
Naropin
Drug Type
Small Molecule
Chemical Formula
C17H26N2O
CAS Number
84057-95-4
Unique Ingredient Identifier
7IO5LYA57N
Background

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication

Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions
Acute Pain, Postoperative pain
Associated Therapies
Surgical anesthesia therapy
Clinical Trials
Related News

Scalp Nerve Block on Emergence Agitation

Phase 4
Completed
Conditions
Agitation
Interventions
Drug: Ropivacaine
Drug: Remifentanil
Drug: Sevoflurane
First Posted Date
2015-04-28
Last Posted Date
2017-01-25
Lead Sponsor
Ajou University School of Medicine
Target Recruit Count
44
Registration Number
NCT02428283
Locations
🇰🇷

Ajou University Hospital, Suwon, Gyeongki-do, Korea, Republic of

Interscalene Brachial Plexus Block Combined With Suprascapular Nerve Block

Not Applicable
Completed
Conditions
Rotator Cuff Injury
Interventions
Device: Ultrasound-guided ISB
Device: Arthroscopy-guided SSNB
Drug: Placebo
Drug: Ropivacaine
First Posted Date
2015-04-23
Last Posted Date
2020-08-27
Lead Sponsor
Chuncheon Sacred Heart Hospital
Target Recruit Count
52
Registration Number
NCT02424630

Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean Section

Phase 3
Completed
Conditions
Postoperative Pain
Interventions
Drug: Morphine
Drug: Ropivacaine
First Posted Date
2015-04-07
Last Posted Date
2022-11-08
Lead Sponsor
University Hospital, Grenoble
Target Recruit Count
101
Registration Number
NCT02410317
Locations
🇫🇷

Hôpital Couple Enfant - CHU de Grenoble, Grenoble, France

MIRs03: Paravertebral Block With Ropivacaine Before Breast Cancer Surgery

Phase 3
Completed
Conditions
Malignant Neoplasm of Breast
Interventions
Drug: Saline
Drug: Ropivacaine
First Posted Date
2015-04-03
Last Posted Date
2019-07-10
Lead Sponsor
Institut Curie
Target Recruit Count
380
Registration Number
NCT02408393
Locations
🇫🇷

INSTITUT CURIE - Site Paris, Paris, France

🇫🇷

Centre Léon Bérard, Lyon, France

🇫🇷

Institut de Cancérologie de Lorraine, Vandoeuvre-les-nancy, France

and more 3 locations

Anesthesia And Post-operative Mortality After Proximal Femur Fractures

Not Applicable
Terminated
Conditions
Hip Fractures
Interventions
Procedure: PNB/GA
Procedure: Subarachnoid Anesthesia
Drug: bupivacaine or levobupivacaine
Drug: ropivacaine
Drug: sevoflurane or desflurane
First Posted Date
2015-04-02
Last Posted Date
2021-02-01
Lead Sponsor
Centro Hospitalar do Porto
Target Recruit Count
57
Registration Number
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Locations
🇵🇹

Serviço de Anestesiologia - Centro Hospitalar do Porto, Porto, Portugal

Effect of Epidural Analgesia on the Length of Labor and Delivery and Fetal Outcomes

Conditions
Labor
Epidural Analgesia
Nulliparous
Interventions
Procedure: epidural analgesia
Drug: Ropivacaine
First Posted Date
2015-03-24
Last Posted Date
2016-03-09
Lead Sponsor
University of Cagliari
Target Recruit Count
100
Registration Number
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Supraclavicular Brachial Plexus Block Using Ropivacaine Alone and With Dexmedetomidine

Not Applicable
Completed
Conditions
Brachial Plexus Anesthesia
Interventions
Drug: Ropivacaine with Dexmedetomidine
Drug: Ropivacaine
First Posted Date
2015-03-19
Last Posted Date
2015-11-06
Lead Sponsor
Government Medical College, Haldwani
Target Recruit Count
80
Registration Number
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A Comparative Study of the Effect of Epidural Dexmedetomidine Versus Fentanyl Added to Ropivacaine in Pediatric Orthopedic Surgery

Not Applicable
Completed
Conditions
Congenital Skelectal Anomaly
Interventions
Drug: fentanyl
Drug: dexmedetomidine
Drug: Ropivacaine
First Posted Date
2015-03-02
Last Posted Date
2016-08-17
Lead Sponsor
Yonsei University
Target Recruit Count
58
Registration Number
NCT02375191
Locations
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Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea, Republic of

The Analgesic Effect of Combined Nerve Block and Systemic High Dose Glucocorticoid After Total Knee Arthroplasty.

Phase 4
Completed
Conditions
Peripheral Nerve Block
Pain
Interventions
Drug: Ropivacaine
First Posted Date
2015-02-27
Last Posted Date
2015-11-30
Lead Sponsor
Regionshospitalet Silkeborg
Target Recruit Count
74
Registration Number
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Exparel vs Exparel Plus ACB in TKAs

Phase 4
Withdrawn
Conditions
Knee Osteoarthritis
Interventions
Drug: Liposomal bupivacaine
Drug: Saline
Drug: Ropivacaine
Drug: Epinephrine
Drug: Clonidine
First Posted Date
2015-02-19
Last Posted Date
2016-01-14
Lead Sponsor
The Hawkins Foundation
Registration Number
NCT02365727
Locations
🇺🇸

Steadman Hawkins Clinic of the Carolinas - Greenville Health System, Greenville, South Carolina, United States

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