MedPath

Bradykinin

Generic Name
Bradykinin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C50H73N15O11
CAS Number
58-82-2
Unique Ingredient Identifier
S8TIM42R2W
Background

Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.

Associated Conditions
-
Associated Therapies
-

Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1

Phase 4
Active, not recruiting
Conditions
Hypertension
Interventions
First Posted Date
2018-11-13
Last Posted Date
2024-03-05
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
32
Registration Number
NCT03738878
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Comparative Effects of Aspirin and NHP-544C

Not Applicable
Completed
Conditions
Healthy
Interventions
Drug: Bradykinin
Drug: Aspirin 81 mg
Drug: NHP544-C 81 mg
Drug: Aspirin 162 mg
Drug: NHP544C 162 mg
Drug: Placebo
First Posted Date
2014-07-14
Last Posted Date
2016-07-12
Lead Sponsor
Vanderbilt University
Target Recruit Count
61
Registration Number
NCT02189122
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Pharmacogenetics of Ace Inhibitor-Associated Angioedema

First Posted Date
2011-08-10
Last Posted Date
2015-11-04
Lead Sponsor
Vanderbilt University
Target Recruit Count
44
Registration Number
NCT01413542
Locations
🇺🇸

Vanderbilt University- General Clinic Research Center, Nashville, Tennessee, United States

Tissue-Type Plasminogen Activator (t-PA) Release Predicts Major Adverse Cardiac Events (MACE) in Patients With Non-critical Coronary Artery Disease

Phase 1
Terminated
Conditions
Coronary Artery Disease
Interventions
First Posted Date
2009-03-25
Last Posted Date
2017-12-13
Lead Sponsor
Vanderbilt University
Target Recruit Count
16
Registration Number
NCT00868855
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Brachial Artery t-PA Release in Heart Transplant Recipients

Not Applicable
Withdrawn
Conditions
Heart Transplantation
Interventions
First Posted Date
2008-10-27
Last Posted Date
2016-07-15
Lead Sponsor
Vanderbilt University
Registration Number
NCT00780637
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Intracoronary Bradykinin Mediated t-PA Release in Heart Transplant Recipients

Not Applicable
Withdrawn
Conditions
Heart Transplantation
Interventions
First Posted Date
2008-10-27
Last Posted Date
2017-03-20
Lead Sponsor
Vanderbilt University
Registration Number
NCT00780377
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Characterization of Brachial Arterial t-PA Release, Endothelial Function, Obesity and Inflammation

Not Applicable
Terminated
Conditions
Obesity
Interventions
First Posted Date
2008-10-27
Last Posted Date
2017-07-14
Lead Sponsor
Vanderbilt University
Target Recruit Count
13
Registration Number
NCT00780481
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Endothelial Hyperpolarization in Humans

First Posted Date
2005-09-14
Last Posted Date
2018-08-15
Lead Sponsor
Emory University
Target Recruit Count
174
Registration Number
NCT00166166
Locations
🇺🇸

Emory University School of Medicine, Atlanta, Georgia, United States

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