Acetaminophen

Generic Name: Acetaminophen

Brand Names: Acephen, Acetadryl, Allzital, Apadaz, Arthriten Inflammatory Pain, Bupap, Butapap, Cetafen, Children's Silapap, Coricidin Hbp Cold & Flu, Darvocet-N, Dayquil Sinex, Diphen, Dolofin, Dologen, Dologesic Reformulated Jun 2016, Duralgina, Dvorah, Endocet, Esgic, Exaprin, Excedrin, Excedrin PM Triple Action, Excedrin Tension Headache, Feverall, Fioricet, Fioricet With Codeine, Goody's Back & Body Pain Relief, Goody's Body Pain, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Hycet, Legatrin PM, Little Fevers, Lorcet, Lortab, Mapap, Mersyndol, Midol Complete, Midol Cramps & Bodyaches, Nalocet, Norco, Orbivan, Pamprin Max Formula, Pamprin Multi-symptom, Panadol, Pediacare Children's Fever Reducer Pain Reliever, Percocet, Percogesic Reformulated Jan 2011, Pharbetol, Premsyn Pms, Prolate, Rivacocet, Robaxacet, Robaxacet-8, Roxicet, Sudafed PE Sinus Headache, Tactinal, Tencon, Trezix, Triatec, Triatec-30, Triatec-8, Tylenol, Tylenol PM, Tylenol With Codeine, Ultracet, Vanatol, Vanatol S, Vanquish, Xodol, Xolox, Zamicet, Zflex, Zydone

Drug Type: Small Molecule

Chemical Formula: C_₈H_₉NO_₂

CAS Number: 103-90-2

Unique Ingredient Identifier: 362O9ITL9D

Background: Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA in 1951 and is available in a var...

Indication: In general, acetaminophen is used for the treatment of mild to moderate pain and reduction of fever. It is available over the counter in various forms, the most common being oral forms.
...

Associated Conditions: Acute Gouty Arthritis, Acute Musculoskeletal Pain, Allergic Reaction, Allergy to Tree Pollen, Ankylosing Spondylitis (AS), Chills, Cold, Common Cold, Cough, Cough caused by Common Cold, Coughing caused by Flu caused by Influenza, Dyskinesia of the Biliary Tract, Dyskinesia of the Urinary Tract, Febrile Convulsions, Febrile Illness Acute, Fever, Fibromyalgia, Flu caused by Influenza, Headache, Joint dislocations, Menstrual Distress (Dysmenorrhea), Mild pain, Muscle Inflammation, Muscle Injuries, Muscle Spasms, Musculoskeletal Pain, Myalgia, Nasal Congestion, Neuropathic Pain, Osteoarthritis (OA), Pain, Postoperative pain, Premenstrual cramps, Rheumatoid Arthritis, Rhinopharyngitis, Rhinorrhoea, Severe Pain, Sinusitis, Spasms, Spastic Pain of the Gastrointestinal Tract, Sprains, Symptoms Cold, Tension Headache, Toothache, Upper Respiratory Tract Infection, Whiplash Syndrome, Acute Torticollis, Articular inflammation, Cold or flu syndrome, Mild to moderate pain, Minor aches and pains, Minor pain, Moderate Pain, Moderate to severe pain

Associated Therapies: Airway secretion clearance therapy, Anti-spasmodics, Bronchodilation

Clinical Trials

Allogeneic Transplantation From Related Haploidentical Donors

Phase 2

Completed

Conditions: Leukemia
Graft Versus Host Disease
NHL
CLL
MDS
Malignancy
Blood Cancer
Hodgkin's Disease

Interventions: Procedure: non-myeloablative hematopoietic cell transplantation
Drug: Anti-Thymocyte Globulin
Drug: Cyclosporine
Drug: Mycophenolate Mofetil
Drug: G-CSF
Drug: Solumedrol
Drug: Acetaminophen
Drug: Diphenydramine
Drug: Hydrocortisone

First Posted Date: 2005-09-16

Last Posted Date: 2019-12-04

Lead Sponsor: Stanford University

Target Recruit Count: 16

Registration Number: NCT00185692

Locations: 🇺🇸
Stanford University School of Medicine, Stanford, California, United States

Phase 2 Trial of Prophylactic Rituximab Therapy for Prevention of CGVHD

Phase 2

Completed

Conditions: Leukemia, Mast-Cell
Mantle-cell Lymphoma

Interventions: Procedure: Total lymphoid irradiation
Drug: Rituximab
Drug: Anti-thymoglobulin, rabbit (ATG, rabbit ATG)
Drug: Cyclosporine
Drug: Mycophenylate mofetil
Drug: Filgrastim
Drug: Granisetron
Drug: Solumedrol
Drug: Acetaminophen
Drug: Diphenhydramine
Drug: Hydrocortisone

First Posted Date: 2005-09-16

Last Posted Date: 2017-11-28

Lead Sponsor: Stanford University

Target Recruit Count: 36

Registration Number: NCT00186628

Locations: 🇺🇸
Stanford University School of Medicine, Stanford, California, United States

Acetaminophen for Cancer Pain

Phase 3

Completed

Conditions: Pain
Cancer

Interventions: Drug: acetaminophen
Drug: placebo, sugar pill

First Posted Date: 2005-09-09

Last Posted Date: 2016-03-08

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 12

Registration Number: NCT00152854

Locations: 🇦🇺
Sydney Cancer Centre, Sydney, New South Wales, Australia
🇨🇦
Princess Margaret Hospital, Toronto, Ontario, Canada

A Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Systemic Lupus Erythematosus

Phase 2

Completed

Conditions: Lupus Erythematosus, Systemic

Interventions: Drug: Rituximab
Drug: Placebo
Drug: Prednisone
Drug: Acetaminophen
Drug: Diphenhydramine

First Posted Date: 2005-08-30

Last Posted Date: 2019-08-20

Lead Sponsor: Genentech, Inc.

Target Recruit Count: 262

Registration Number: NCT00137969

Locations: 🇺🇸
Univ of Calif., Los Angeles; Rheumatology, Los Angeles, California, United States
🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States
🇺🇸
Emory Uni ; Division of Rheumatology, Atlanta, Georgia, United States

and more 62 locations

Glucosamine Unum In Die [Once A Day] Efficacy (GUIDE) Trial: Glucosamine Sulfate in Patients With Knee Osteoarthritis

Phase 3

Completed

Conditions: Knee Osteoarthritis

First Posted Date: 2005-05-10

Last Posted Date: 2006-09-19

Lead Sponsor: Rottapharm

Target Recruit Count: 300

Registration Number: NCT00110474

Locations: 🇵🇹
Hospital Universitario de Coimbra, Coimbra, Portugal
🇵🇹
Hospital Egaz Moniz, Lisboa, Portugal
🇵🇹
Hospital Conde do Bertiandos, Ponte de Lima, Portugal

and more 10 locations