Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Prevention of Shivering Associated With Spinal Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2023-10-13
- Last Posted Date
- 2023-10-13
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 90
- Registration Number
- NCT06082076
Evaluation of the Hemodynamic Effect of Dexmedetomidine in Scheduled Outpatient Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-10-13
- Last Posted Date
- 2023-11-29
- Lead Sponsor
- Centre Hospitalier Universitaire de Nīmes
- Target Recruit Count
- 594
- Registration Number
- NCT06082856
- Locations
- 🇫🇷
CHU de Nîmes, Nîmes, France
Adjuvants With Intrathecal Bupivacaine for Postoperative Analgesia
- Conditions
- Interventions
- First Posted Date
- 2023-10-13
- Last Posted Date
- 2023-10-16
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 90
- Registration Number
- NCT06082232
Dexmedetomidine Versus Ketamine Versus Magnesium Sulfate for the Prevention of Emergence Agitation Following Sevoflurane Induced Anesthesia in Cardiac Catheterization in Pediatrics
- Conditions
- Interventions
- First Posted Date
- 2023-10-11
- Last Posted Date
- 2023-10-11
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 100
- Registration Number
- NCT06077539
- Locations
- 🇪🇬
Amany Hassan Saleh, Giza, Egypt
Dexmedetomidine Infusion Versus Oral Melatonin for Prevention of Intensive Care Delirium
- Conditions
- Interventions
- First Posted Date
- 2023-10-11
- Last Posted Date
- 2023-10-17
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 90
- Registration Number
- NCT06076668
- Locations
- 🇪🇬
Tanta University, Tanta, El-Gharbia, Egypt
Intranasal Dexmedetomidine for Pain Management During Screening for Retinopathy of Prematurity
- Conditions
- Interventions
- First Posted Date
- 2023-10-05
- Last Posted Date
- 2024-12-06
- Lead Sponsor
- Assaf-Harofeh Medical Center
- Target Recruit Count
- 30
- Registration Number
- NCT06067958
- Locations
- 🇮🇱
Assaf-Harofeh Medical Center, Be'er Ya'akov, Center, Israel
Low Dose Dexmedetomidine as a Postoperative Pain Adjunct
- Conditions
- Interventions
- First Posted Date
- 2023-10-05
- Last Posted Date
- 2024-08-02
- Lead Sponsor
- Children's Mercy Hospital Kansas City
- Target Recruit Count
- 160
- Registration Number
- NCT06067893
- Locations
- 🇺🇸
Children's Mercy Hospital, Kansas City, Missouri, United States
Regional Anaesthesia
- Conditions
- Interventions
- First Posted Date
- 2023-09-26
- Last Posted Date
- 2023-09-26
- Lead Sponsor
- Reham Ali Abdelhaleem Abdelrahman
- Target Recruit Count
- 54
- Registration Number
- NCT06055101
- Locations
- 🇪🇬
Reham Ali Abdelrahman, Cairo, Egypt
Dexmedetomidine Infusion During Laparoscopic Adrenalectomy
- Conditions
- Interventions
- First Posted Date
- 2023-09-14
- Last Posted Date
- 2023-10-06
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 40
- Registration Number
- NCT06037135
- Locations
- 🇰🇷
Severance hospital, Seoul, Korea, Republic of
Perioperative Dexmedetomidine and Long-term Survival After Cancer Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-09-11
- Last Posted Date
- 2023-12-29
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 4532
- Registration Number
- NCT06030804
- Locations
- 🇨🇳
Peking University Shenzhen Hospital, Shenzhen, Guangdong, China
🇨🇳The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China
🇨🇳The First Affiliated Hospital of China University of Science and Technology(Anhui Provincial Hospital), Hefei, Hebei, China
Drug Development Updates
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