Dexmedetomidine

Generic Name
Dexmedetomidine
Brand Names
Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
Drug Type
Small Molecule
Chemical Formula
C13H16N2
CAS Number
113775-47-6
Unique Ingredient Identifier
67VB76HONO
Background

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

Indication

Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.

Associated Conditions
Agitation, Alcohol Withdrawal Syndrome
Associated Therapies
-
Clinical Trials
Related News

Hemodynamic Responses of Dexmedetomidine, Lidocaine or Propofol Infusions During Laparoscopic Cholecystectomy

First Posted Date
2023-07-10
Last Posted Date
2023-07-11
Lead Sponsor
Menoufia University
Target Recruit Count
80
Registration Number
NCT05937282
Locations
🇪🇬

Menoufia University, Shibīn Al Kawm, Menoufia, Egypt

The Effect of Remimazolam and Dexmedetomidine on the Incidence of Hypotension During Spinal Anesthesia

Not Applicable
Not yet recruiting
Conditions
Spinal Anesthesia
Remimazolam
Interventions
Drug: Remimazolam
Drug: Dexmedetomidine
First Posted Date
2023-07-07
Last Posted Date
2023-08-08
Lead Sponsor
Pusan National University Yangsan Hospital
Target Recruit Count
72
Registration Number
NCT05935657

Dexmedetomidine and Kidney Transplantation

Phase 4
Not yet recruiting
Conditions
Dexmedetomidine
Renal Transplantation
Interventions
Drug: Dexmedetomidine
First Posted Date
2023-07-07
Last Posted Date
2024-05-08
Lead Sponsor
Eduardo Schiffer
Target Recruit Count
206
Registration Number
NCT05935293

Evaluation of Renal Protection Of Dexmedetomidine Versus Midazolam As a Sedative For Septic Patients In Intensive Care Unit

Phase 1
Recruiting
Conditions
Renal Failure
Interventions
Drug: Midazolam
Drug: dexmedetomidine
First Posted Date
2023-06-15
Last Posted Date
2023-06-15
Lead Sponsor
Minia University
Target Recruit Count
40
Registration Number
NCT05903963
Locations
🇪🇬

Marlin Zarif Shehata, Minya, Egypt

Comparisons Between Dexmedetomidine and Magnesium Sulfate in Controlled Hypotension During Rhinoplasty Surgeries

Phase 1
Completed
Conditions
Hypotension
Interventions
Drug: Dexmedetomidine
Drug: Magnesium sulfate
First Posted Date
2023-05-30
Last Posted Date
2023-05-31
Lead Sponsor
mohamed
Target Recruit Count
56
Registration Number
NCT05880693
Locations
🇪🇬

Mohamed gawad Abdel aboelsuod, Cairo, Egypt

Propofol Versus Dexmedetomidine on the Incidence of Postoperative Nausea and Vomiting

Not Applicable
Recruiting
Conditions
Nausea and Vomiting, Postoperative
Interventions
Drug: Propofol
Drug: Dexmedetomidine
First Posted Date
2023-05-25
Last Posted Date
2023-08-31
Lead Sponsor
Cairo University
Target Recruit Count
45
Registration Number
NCT05875077
Locations
🇪🇬

Kasralaini Medical School, Cairo, Egypt

Comparing the Hemodynamic Effects of Epinephrine Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Caudal Anaesthesia Assessed by Cardiometry

Not Applicable
Not yet recruiting
Conditions
Anesthesia, Local
Interventions
Drug: Epinephrine injection
Drug: Dexmedetomidine
Drug: Bupivacaine
First Posted Date
2023-05-16
Last Posted Date
2023-05-16
Lead Sponsor
Kasr El Aini Hospital
Target Recruit Count
39
Registration Number
NCT05860010
Locations
🇪🇬

Kasr Al Ainy, Cairo, Egypt

🇪🇬

Ayman Abougabal [aabougabal], Cairo, Egypt

Dexmedetomidinine in the Prevention of Postoperative Delirium in the Intensive Care Unit After Cardiac Surgery

First Posted Date
2023-05-09
Last Posted Date
2024-12-04
Lead Sponsor
University of Novi Sad
Target Recruit Count
200
Registration Number
NCT05849597
Locations
🇷🇸

Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia

Opioid-sparing Effect of Intranasal Dexmedetomidine

Not Applicable
Completed
Conditions
Tonsillar Hypertrophy
Interventions
Drug: Dexmedetomidine
First Posted Date
2023-05-08
Last Posted Date
2023-05-08
Lead Sponsor
Pierre-Yves P Lequeux
Target Recruit Count
50
Registration Number
NCT05848505
Locations
🇦🇪

Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates

Dexmedetomidine, Ketamine and Magnesium Sulphate in Caudal Block for Hypospadias Repair

First Posted Date
2023-05-01
Last Posted Date
2023-06-13
Lead Sponsor
Kafrelsheikh University
Target Recruit Count
75
Registration Number
NCT05837000
Locations
🇪🇬

Karelsheikh University Hospital, Kafr Ash Shaykh, Karelsheikh, Egypt

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