Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
Beneficial Effects of Low-Dose Intravenous Dexmedetomidine Premedication in Patient Undergoing Laparoscopic Cholecystectomy Under General Anesthesia
- Conditions
- Laparoscopic Cholecystectomy Surgery
- Interventions
- Drug: Saline
- First Posted Date
- 2025-02-21
- Last Posted Date
- 2025-02-21
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 100
- Registration Number
- NCT06838650
Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty
- Conditions
- Intrathecal DexmedetomidineAdductor Canal BlockAnalgesiaTotal Knee Arthroplasty
- Interventions
- Drug: Adductor Canal BlockDrug: Intrathecal Dexmedetomidine + Adductor Canal Block
- First Posted Date
- 2025-02-20
- Last Posted Date
- 2025-02-21
- Lead Sponsor
- Kafrelsheikh University
- Target Recruit Count
- 75
- Registration Number
- NCT06837844
- Locations
- 🇪🇬
Kafrelsheikh University, Kafr Ash Shaykh, Kafrelsheikh, Egypt
Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery
- Conditions
- LidocaineDexmedetomidineInfusionPerioperative PainVideo-Assisted Thoracoscopic Surgery
- Interventions
- First Posted Date
- 2025-02-20
- Last Posted Date
- 2025-02-21
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 75
- Registration Number
- NCT06837519
- Locations
- 🇪🇬
Ain Shams University, Cairo, Egypt
To Explore the Optimal Dose of Dexmedetomidine for Skull Pin Fixation in Intracranial Surgery
- First Posted Date
- 2025-02-20
- Last Posted Date
- 2025-02-20
- Target Recruit Count
- 40
- Registration Number
- NCT06837818
Sevoflurane and Dexmedetomidine's Contrasting Renal Impacts After Non-Cardiac Surgery
- Conditions
- AKI - Acute Kidney Injury
- Interventions
- First Posted Date
- 2025-02-19
- Last Posted Date
- 2025-02-19
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 90
- Registration Number
- NCT06835010
- Locations
- 🇪🇬
Tanta University, Tanta, El Gharbyia, Egypt
Dexmedetomidine and Fentanyl As Adjuvants to Hyperbaric Bupivacaine for the Prevention of Post-spinal Shivering in Hip Arthroplasty Surgeries
- Conditions
- Post Spinal Shivering
- Interventions
- First Posted Date
- 2025-02-19
- Last Posted Date
- 2025-02-19
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 100
- Registration Number
- NCT06834841
- Locations
- 🇪🇬
Ain Shams University, Cairo, Egypt
Reducing Days DELirious With DEXmedetomidine as Part of an Intensive Care Unit Sleep Promotion Bundle
- Conditions
- SleepDeliriumICU Hospitalization
- Interventions
- Other: Control (placebo) group
- First Posted Date
- 2025-02-13
- Last Posted Date
- 2025-04-15
- Lead Sponsor
- University of Alberta
- Target Recruit Count
- 50
- Registration Number
- NCT06824077
Comparative Analysis of Analgesic Efficacy and Maternal Satisfaction: by Single Shot Intrathecal Analgesia (SSSA) in Normal Labor
- Conditions
- Vaginal DeliveryNormal Labor
- Interventions
- First Posted Date
- 2025-02-12
- Last Posted Date
- 2025-03-07
- Lead Sponsor
- Jehan George Sadek
- Target Recruit Count
- 90
- Registration Number
- NCT06823349
- Locations
- 🇪🇬
Aswan University Hospital, Aswan, Egypt
Effects of Esketamine on Oxygenation and Quality of Recovery in Patients Undergoing Thoracoscopic Surgery
- Conditions
- EsketamineOne-lung VentilationOxygenation Indices
- Interventions
- First Posted Date
- 2025-02-12
- Last Posted Date
- 2025-02-12
- Lead Sponsor
- Jinqiao Qian
- Target Recruit Count
- 126
- Registration Number
- NCT06822088
- Locations
- 🇨🇳
The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
Dexmedetomidine an Effective Drug in Reducing Anesthetic Requirements in External Dacrocystorhinostomy (DCR) Patients
- Conditions
- Patients Undergoing External Dacrocystorhinostomy OperationsAssess Decreased Anesthetic Requirements Intraoperative
- Interventions
- First Posted Date
- 2025-02-05
- Last Posted Date
- 2025-02-05
- Lead Sponsor
- Research Institute of Ophthalmology, Egypt
- Target Recruit Count
- 24
- Registration Number
- NCT06808295
- Locations
- 🇪🇬
Research Institute of Ophthalmolgy, Giza, Egypt
Drug Development Updates
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