Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film...
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Comparative Study of Opioid-Free Anesthesia Versus Opioid Anesthesia in Patients Undergoing Laparoscopic Cholecystectomy
- Conditions
- Interventions
- First Posted Date
- 2024-12-16
- Last Posted Date
- 2024-12-16
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 100
- Registration Number
- NCT06736496
Comparing the Synergistic Effect of Caudal Dexmedetomidine and Propofol Versus Caudal Dexmedetomidine Only or Propofol Only in Prevention of Sevoflurane Related Emergence Agitation in Pediatric Patients Undergoing Congenital Inguinal Hernia Repair
- Conditions
- Interventions
- First Posted Date
- 2024-12-16
- Last Posted Date
- 2024-12-16
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 90
- Registration Number
- NCT06734195
Intravenous Dexmedetomidine As an Adjuvant to Locoregional Anesthesia in Pediatric Surgery
- Conditions
- Interventions
- First Posted Date
- 2024-12-16
- Last Posted Date
- 2024-12-16
- Lead Sponsor
- University Hospital, Montpellier
- Target Recruit Count
- 200
- Registration Number
- NCT06736483
Comparative Study Between the Analgesic Effect of Dexmedetomidine and Magnesium Sulfate As Adjuvant to Bupivacaine Using Ultrasound-Guided Transversus Abdominis Plane Block in Abdominal Hysterectomy : a Randomized Double-blinded Study
- Conditions
- Interventions
- First Posted Date
- 2024-12-06
- Last Posted Date
- 2024-12-06
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 64
- Registration Number
- NCT06720337
Role of Intravenous Dexmedetomidine in Reducing Shivering After Shivering Cesarean Section Due to Spinal Anesthesia
- First Posted Date
- 2024-12-02
- Last Posted Date
- 2024-12-02
- Lead Sponsor
- Liaquat National Hospital & Medical College
- Target Recruit Count
- 60
- Registration Number
- NCT06711913
- Locations
- 🇵🇰
Liaquat National Hospital and Medical College, Karachi, Sindh, Pakistan
Dexmedetomidine and Magnesium Sulfate in the Reduction Cognitive Dysfunction in Geriatrics
- First Posted Date
- 2024-11-25
- Last Posted Date
- 2024-11-25
- Lead Sponsor
- Fayoum University
- Target Recruit Count
- 58
- Registration Number
- NCT06702488
- Locations
- 🇪🇬
Dexmedetomidine, Fayoum, Egypt
Comparing the Effect of Adding Dexmedetomidine to Bupivacaine in Classical and Modified Thoracolumbar Interfascial Plane Block on Postoperative Pain in Patients Undergoing Lumbar Disc Surgeries
- First Posted Date
- 2024-11-15
- Last Posted Date
- 2024-11-15
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 26
- Registration Number
- NCT06690021
Dexmedetomidine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain
- Conditions
- Interventions
- First Posted Date
- 2024-11-12
- Last Posted Date
- 2024-11-15
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 40
- Registration Number
- NCT06684535
- Locations
- 🇪🇬
Tanta University, Tanta, El-Gharbia, Egypt
Dexmedetomidine for Improved Pain Relief and Recovery in Spine Surgery
- Conditions
- Interventions
- First Posted Date
- 2024-11-12
- Last Posted Date
- 2024-11-12
- Lead Sponsor
- Menoufia University
- Target Recruit Count
- 150
- Registration Number
- NCT06685081
- Locations
- 🇪🇬
Menoufia University, Shibīn Al Kawm, El Menoufia, Egypt
The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil Consumption
- Conditions
- Interventions
- First Posted Date
- 2024-11-12
- Last Posted Date
- 2024-11-12
- Lead Sponsor
- Ciusss de L'Est de l'Île de Montréal
- Target Recruit Count
- 72
- Registration Number
- NCT06684197
- Locations
- 🇨🇦
Hôpital Maisonneuve-Rosemont, Montréal, Quebec, Canada
Drug Development Updates
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