Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
Dexmedetomidine Versus Fentanyl As Adjuvants to Erector Spinae Plane Block for Postoperative Analgesia Following Simple Nephrectomy: a Randomized Clinical Trial
- Conditions
- Nephrectomy
- Interventions
- First Posted Date
- 2025-01-29
- Last Posted Date
- 2025-01-29
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 46
- Registration Number
- NCT06799442
- Locations
- 🇪🇬
Assiut University, Assiut, Egypt
Postoperative Cognitive Dysfunction in Transsphenoidal Pituitary Surgeries
- Conditions
- Cognitive DysfunctionOpioid Free Anesthesia
- Interventions
- First Posted Date
- 2025-01-27
- Last Posted Date
- 2025-01-27
- Lead Sponsor
- Kocaeli University
- Target Recruit Count
- 48
- Registration Number
- NCT06793150
- Locations
- 🇹🇷
Kocaeli University, Kocaeli, Turkey
Dexmedetomidine for ESPB in Pain Management After Pediatric Idiopathic Scoliosis Surgery
- Conditions
- Scoliosis IdiopathicScoliosisScoliosis; Adolescence
- Interventions
- Drug: 0.9%NaCl
- First Posted Date
- 2025-01-23
- Last Posted Date
- 2025-01-23
- Lead Sponsor
- Poznan University of Medical Sciences
- Target Recruit Count
- 60
- Registration Number
- NCT06789016
- Locations
- 🇵🇱
Department of Spine Diseases and Pediatric Orthopedics, University of Medical Sciences, Poznań, Poland, Poznań, Wielkopolska, Poland
Comparison of the Efficacy of Bupivacaine with and Without Dexmedetomidine As an Adjuvant on Penile Block for Postoperative Pain Relief in Pediatrics Undergoing Hypospadias Repair Surgery
- Conditions
- Hypospadias Repair Surgery
- Interventions
- First Posted Date
- 2025-01-23
- Last Posted Date
- 2025-01-23
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 80
- Registration Number
- NCT06789393
Comparative Study of Fentanyl vs Dexmedetomidine as Adjuvants to Intrathecal Bupivacaine in Cesarean Section
- First Posted Date
- 2025-01-21
- Last Posted Date
- 2025-01-21
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 60
- Registration Number
- NCT06785285
- Locations
- 🇪🇬
Sohag University Hospital, Sohag, Egypt
Intravenous Granisetron Vs Dexmedetomidine on Postspinal in the Cesarean Section.
- Conditions
- Postspinal Shivering
- Interventions
- First Posted Date
- 2025-01-08
- Last Posted Date
- 2025-01-09
- Lead Sponsor
- Minia University
- Target Recruit Count
- 99
- Registration Number
- NCT06762860
- Locations
- 🇪🇬
Minya University Faculty of Medicine, Minya, Egypt
DISE in Pediatric Sleep Disordered Breathing
- Conditions
- Sleep Disordered BreathingDrug Induced Sleep Disorder
- Interventions
- First Posted Date
- 2025-01-03
- Last Posted Date
- 2025-01-03
- Lead Sponsor
- University of Iowa
- Registration Number
- NCT06756971
Dexmedetomidine Nasal Spray and Pediatric Bronchoscopy
- Conditions
- Fiberoptic Bronchoscopy
- Interventions
- First Posted Date
- 2025-01-01
- Last Posted Date
- 2025-05-07
- Lead Sponsor
- Tongji Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT06755996
- Locations
- 🇨🇳
Tongji hospital, Wuhan, Hubei, China
Effect of Remimazolam Versus Dexmedetomidine on the Incidence of Delirium After Elective Cardiac Surgery with Cardiopulmonary Bypass: a Prospective Randomized Controlled Trial
- Conditions
- Delirium - Postoperative
- Interventions
- First Posted Date
- 2025-01-01
- Last Posted Date
- 2025-01-01
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 111
- Registration Number
- NCT06756178
- Locations
- 🇪🇬
Assiut University, Assiut, Egypt
Acute Agitation in Emergency Psychiatry
- Conditions
- Agitation
- Interventions
- First Posted Date
- 2024-12-30
- Last Posted Date
- 2025-01-01
- Lead Sponsor
- Lone Baandrup
- Target Recruit Count
- 132
- Registration Number
- NCT06752616
- Locations
- 🇩🇰
Mental Health Center Copenhagen, Bispebjerg, Copenhagen N, Denmark
Drug Development Updates
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