Parecoxib
- Generic Name
- Parecoxib
- Brand Names
- Dynastat
- Drug Type
- Small Molecule
- Chemical Formula
- C19H18N2O4S
- CAS Number
- 198470-84-7
- Unique Ingredient Identifier
- 9TUW81Y3CE
- Background
Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral medications. It is approved through much of Europe for short term perioperative pain control much in the same way ketorolac (Toradol) is used in the United States. A letter of non-approval for parecoxib was issued by the FDA in 2005.
- Indication
Used for short term perioperative pain control.
- Associated Conditions
- Postoperative pain
Morphine-Sparing Efficacy Of Parecoxib In Pain Treatment After Radical Prostatectomy
- Conditions
- Pain, Postoperative
- Interventions
- Drug: Morphine, Placebo
- First Posted Date
- 2006-06-29
- Last Posted Date
- 2011-10-28
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 105
- Registration Number
- NCT00346268
- Locations
- 🇩🇪
Pfizer Investigational Site, Reutlingen, Germany
Morphine-Sparing Effect And Safety Of Parecoxib Administered Intravenously For The Treatment Of Postoperative Pain
- Conditions
- Pain, Postoperative
- First Posted Date
- 2005-09-02
- Last Posted Date
- 2008-04-15
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 220
- Registration Number
- NCT00143169
- Locations
- 🇨🇳
Pfizer Investigational Site, Shanghai, China
Parecoxib in Renal Colic
- Conditions
- Colic
- First Posted Date
- 2005-08-31
- Last Posted Date
- 2008-05-06
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 50
- Registration Number
- NCT00139646
- Locations
- 🇮🇹
Pfizer Investigational Site, Siena, Italy
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.