Mupirocin

Generic Name
Mupirocin
Brand Names
Bactroban, Centany, Pirnuo
Drug Type
Small Molecule
Chemical Formula
C26H44O9
CAS Number
12650-69-0
Unique Ingredient Identifier
D0GX863OA5
Background

Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and...

Indication

Indicated for the treatment of impetigo and secondary skin infections, leading to traumatic skin lesions, due to Staphylococcus aureus and Streptococcus pyogenes.

Associated Conditions
Impetigo, Impetigo caused by Staphylococcus aureus, Impetigo caused by streptococcus pyogenes, Secondary infection Skin infection, Staphylococcus aurea colonization of the nasal passage
Associated Therapies
-

Efficacy Study of Mupirocin on Infection After Coronary Artery Bypass Grafting

Phase 3
Completed
Conditions
Interventions
First Posted Date
2013-09-25
Last Posted Date
2013-09-25
Lead Sponsor
Horizon Health Network
Target Recruit Count
974
Registration Number
NCT01949935
Locations
🇨🇦

New Brunswick Heart Centre, Saint John Regional Hospital, Saint John, New Brunswick, Canada

Evaluation of a Staphylococcus Eradication Protocol for Patients Who Present to the ED With Cutaneous Abscess

First Posted Date
2012-02-23
Last Posted Date
2017-04-13
Lead Sponsor
Tufts Medical Center
Target Recruit Count
50
Registration Number
NCT01537783
Locations
🇺🇸

Tufts Medical Center, Boston, Massachusetts, United States

Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF)

First Posted Date
2011-05-06
Last Posted Date
2017-05-15
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
47
Registration Number
NCT01349192
Locations
🇺🇸

St. Louis Children's Hospital, St. Louis, Missouri, United States

🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

🇺🇸

The Children's Hospital, Aurora, Colorado, United States

and more 10 locations

MESS-study MRSA Eradication Study Skåne

First Posted Date
2011-01-04
Last Posted Date
2017-08-22
Lead Sponsor
Region Skane
Target Recruit Count
69
Registration Number
NCT01269541
Locations
🇸🇪

Kristianstad hospital, Kristianstad, Skåne, Sweden

🇸🇪

Örebro university hospital, Örebro, Sweden

🇸🇪

SUS Malmö, Malmö, Skåne, Sweden

and more 3 locations

Effect of Intranasal Mupirocin on Rate of Staphylococcus Aureus Surgical Site Infection Following Cesarean Sections

First Posted Date
2010-06-29
Last Posted Date
2010-06-29
Lead Sponsor
Hillel Yaffe Medical Center
Target Recruit Count
400
Registration Number
NCT01152593
Locations
🇮🇱

Hillel Yaffe Medical Center, Hadera, Israel

Prophylaxis With Intranasal Mupirocin for Prevention of S. Aureus Infections

First Posted Date
2005-09-12
Last Posted Date
2010-05-25
Lead Sponsor
University Hospital Muenster
Target Recruit Count
1200
Registration Number
NCT00156377
Locations
🇩🇪

Institute of Medical Microbiology, University Hospital of Muenster, Muenster, Germany

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