MedPath

Isoflurane

Generic Name
Isoflurane
Brand Names
Forane, Terrell
Drug Type
Small Molecule
Chemical Formula
C3H2ClF5O
CAS Number
26675-46-7
Unique Ingredient Identifier
CYS9AKD70P
Background

A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Indication

For induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Induction and Maintenance of General Anesthesia

Cardioprotective Effect of Ketamine-dexmeditomidine Versus Fentanyl-midazolam in Open Heart Surgery in Pediatrics

Phase 1
Completed
Conditions
Anesthesia
Interventions
First Posted Date
2022-04-06
Last Posted Date
2024-02-07
Lead Sponsor
Cairo University
Target Recruit Count
81
Registration Number
NCT05314569
Locations
🇪🇬

Amany Hassan Saleh, Giza, Egypt

Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU1)

Phase 3
Active, not recruiting
Conditions
Sedation
Interventions
First Posted Date
2022-04-05
Last Posted Date
2024-05-03
Lead Sponsor
Sedana Medical
Target Recruit Count
235
Registration Number
NCT05312385
Locations
🇺🇸

Emory University, Atlanta, Georgia, United States

🇺🇸

The Cleveland Clinic Foundation, Cleveland, Ohio, United States

🇺🇸

University of Virginia, Charlottesville, Virginia, United States

and more 11 locations

Effect & Safety of Inhaled Isoflurane vs IV Midazolam for Sedation in Mechanically Ventilated Children 3-17 Years Old

Phase 3
Completed
Conditions
Sedation
Interventions
First Posted Date
2020-12-24
Last Posted Date
2023-04-12
Lead Sponsor
Sedana Medical
Target Recruit Count
97
Registration Number
NCT04684238
Locations
🇫🇷

CHU de NANTES, Hôpital Mère-Enfant, Nantes, France

🇫🇷

Hôpital Robert-Debré AP-HP, Paris, France

🇪🇸

Hospital Infantil Universitario Niño Jesús Pediatric Intensive Care Unit, Madrid, Spain

and more 21 locations

Comparing Quality of Recovery Between Desflurane & Isoflurane in Eye Surgery Patients at Dr George Mukhari Acad Hospital

Not Applicable
Completed
Conditions
Quality of Recovery
Anesthesia Recovery Period
Interventions
First Posted Date
2019-12-05
Last Posted Date
2022-10-18
Lead Sponsor
Sefako Makgatho Health Sciences University
Target Recruit Count
170
Registration Number
NCT04188314
Locations
🇿🇦

Sefako Makgatho Health Sciences University, Ga-Rankuwa, Gauteng, South Africa

Efficacy of Deep Anaesthesia With Isoflurane as a Fast-response Antidepressant Agent

Phase 2
Conditions
Depressive Disorder, Major
Treatment Resistant Depression
Depressive Episode
Interventions
First Posted Date
2019-11-20
Last Posted Date
2019-11-20
Lead Sponsor
University of Sao Paulo
Target Recruit Count
30
Registration Number
NCT04171193
Locations
🇧🇷

Insitute of Psychiatry of the University of São Paulo, São Paulo, Brazil

The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)

Not Applicable
Completed
Conditions
Anesthesia; Adverse Effect
Congenital Heart Disease
Neurodevelopmental Disorders
Interventions
First Posted Date
2019-03-20
Last Posted Date
2022-05-09
Lead Sponsor
Stanford University
Target Recruit Count
153
Registration Number
NCT03882788
Locations
🇺🇸

Stanford Childrens hospital, Palo Alto, California, United States

Different Volatile Anaesthetics and the Depth of Long Term ICU Sedation

Not Applicable
Completed
Conditions
Intensive Care Unit Syndrome
Interventions
First Posted Date
2019-03-01
Last Posted Date
2019-03-01
Lead Sponsor
Ruhr University of Bochum
Target Recruit Count
30
Registration Number
NCT03860129

The Ratio of Hypnotic to Analgesic Potency of Volatile Anesthetics

Phase 3
Completed
Conditions
Anesthesia
Interventions
First Posted Date
2018-07-17
Last Posted Date
2024-04-09
Lead Sponsor
Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine
Target Recruit Count
90
Registration Number
NCT03588429
Locations
🇨🇳

Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou, Hebei, China

Inhaled Anesthetics and Myocardial Strain

Phase 1
Completed
Conditions
Heart Diseases
Interventions
First Posted Date
2018-06-26
Last Posted Date
2023-10-05
Lead Sponsor
Kathirvel Subramaniam
Target Recruit Count
26
Registration Number
NCT03569085
Locations
🇺🇸

UPMC Presbyterian Hospital, Pittsburgh, Pennsylvania, United States

Serun Fluoride and Kidney Transplant

Phase 2
Completed
Conditions
Kidney Transplant; Complications
Interventions
First Posted Date
2017-12-14
Last Posted Date
2017-12-14
Lead Sponsor
Assiut University
Target Recruit Count
30
Registration Number
NCT03373266
Locations
🇪🇬

Assiut university faculty of medicine, Assiut, Egypt

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