Pilocarpine

Generic Name
Pilocarpine
Brand Names
Betoptic Pilo, Isoptocarpine, Minims Pilocarpine Nitrate, Salagen, Vuity
Drug Type
Small Molecule
Chemical Formula
C11H16N2O2
CAS Number
92-13-7
Unique Ingredient Identifier
01MI4Q9DI3
Background

Pilocarpine is a cholinergic muscarinic receptor agonist.

Indication

Pilocarpine oral tablets are indicated for the treatment of dry mouth caused by Sjogren's Syndrome or radiotherapy for cancer of the head and neck.
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Associated Conditions
Acute angle-closure glaucoma, Dry Mouth, Glaucoma, Closed-Angle, Increased Intra Ocular Pressure (IOP), Narrow-angle glaucoma, Ocular Hypertension, Open Angle Glaucoma (OAG), Presbyopia, Chronic open-angle glaucoma
Associated Therapies
-

Bioequivalency Study of 5 mg Pilocarpine Tablets Under Fasting Conditions

Not Applicable
Completed
Conditions
First Posted Date
2008-01-28
Last Posted Date
2018-01-23
Lead Sponsor
Roxane Laboratories
Target Recruit Count
28
Registration Number
NCT00601874
Locations
🇺🇸

CEDRA Clinical Research, LLC, Austin, Texas, United States

Trial Comparing Oral Pilocarpine (Salagen) Versus Submandibular Salivary Gland Transfer Protocol, For the Prevention of Radiation (XRT) Induced Xerostomia in Head and Neck Cancer Patients

Phase 3
Completed
Conditions
First Posted Date
2005-09-15
Last Posted Date
2011-04-18
Lead Sponsor
Alberta Health services
Target Recruit Count
220
Registration Number
NCT00168181
Locations
🇨🇦

Cross Cancer Institute, Edmonton, Alberta, Canada

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