Dopamine

Generic Name: Dopamine

Drug Type: Small Molecule

Chemical Formula: C_₈H_₁₁NO_₂

CAS Number: 51-61-6

Unique Ingredient Identifier: VTD58H1Z2X

Background: One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.

Indication: For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure

Associated Conditions: Arrhythmia, Circulatory collapse and shock, Hypotension caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Urine flow decreased caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Decreased cardiac output caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction

Clinical Trials

L-dopa Versus Dopamine Agonists After Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease

Phase 2

Conditions: Parkinson's Disease

Interventions: Drug: L-dopa
Drug: Dopamine Agonists (pramipexole, ropirinole)

First Posted Date: 2015-01-27

Last Posted Date: 2015-01-27

Lead Sponsor: University of Toronto

Target Recruit Count: 40

Registration Number: NCT02347059

Locations: 🇨🇦
Movement disorders Centre, Toronto Western Hospital, Toronto, Ontario, Canada

The Effect of Norepinephrine and Dopamine on Radial Forearm Free Flap Tissue Oxygen Pressure and Microdialysate Metabolite Measurements

Phase 4

Completed

Conditions: Head and Neck Cancer

Interventions: Drug: Norepinephrine
Other: no medication
Drug: Dopamine

First Posted Date: 2014-09-16

Last Posted Date: 2014-09-16

Lead Sponsor: Tampere University Hospital

Target Recruit Count: 25

Registration Number: NCT02241083

Locations: 🇫🇮
Tampere University Hospital, Tampere, P.O. Box 2000, Finland

Dopamine Rhythms in Health and Addiction

Early Phase 1

Withdrawn

Conditions: Cocaine Abuse

Interventions: Drug: Brain Dopamine Reactivity
Radiation: Brain Dopamine Receptor

First Posted Date: 2014-09-09

Last Posted Date: 2024-04-24

Lead Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Registration Number: NCT02233829

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Impact of Dopamine Infusion on Insulin Secretion in Healthy Subjects

Phase 1

Completed

Conditions: Hyperglycemia
Sepsis

Interventions: Drug: Dopamine

First Posted Date: 2014-02-04

Last Posted Date: 2016-08-09

Lead Sponsor: Albert Einstein College of Medicine

Target Recruit Count: 15

Registration Number: NCT02053935

Locations: 🇺🇸
Montefiore Medical Center of Albert Einstein College of Medicine, Bronx, New York, United States

Vasopressors for Cerebral Oxygenation

Phase 1

Conditions: Hypotension
Hypoxia

Interventions: Drug: dopamine
Drug: phenylephrine

First Posted Date: 2013-12-11

Last Posted Date: 2013-12-11

Lead Sponsor: Samsung Medical Center

Target Recruit Count: 50

Registration Number: NCT02009007

Locations: 🇰🇷
Samsung medical center, Seoul, Korea, Republic of

Diuretics and Dopamine in Heart Failure With Preserved Ejection Fraction

Phase 4

Completed

Conditions: Heart Failure, Diastolic

Interventions: Drug: Furosemide
Drug: Dopamine

First Posted Date: 2013-07-17

Last Posted Date: 2018-08-16

Lead Sponsor: Johns Hopkins University

Target Recruit Count: 90

Registration Number: NCT01901809

Locations: 🇺🇸
Johns Hopkins Hospital, Baltimore, Maryland, United States

Renal Function During Laparoscopic Surgery

Not Applicable

Completed

Conditions: Intra Operative Fluid Management

Interventions: Drug: Dopamine

First Posted Date: 2012-11-07

Last Posted Date: 2012-11-07

Lead Sponsor: Catholic University of the Sacred Heart

Target Recruit Count: 60

Registration Number: NCT01722630

Locations: 🇮🇹
Catholic University of the sacred Heart, Rome, Italy

Management of Hypotension In the Preterm Infant

Phase 3

Terminated

Conditions: Hypotension
Low Blood Pressure
Intraventricular Hemorrhage of Prematurity

Interventions: Drug: Dopamine hydrochloride
Drug: Dextrose 5%

First Posted Date: 2011-11-30

Last Posted Date: 2019-10-02

Lead Sponsor: University College Cork

Target Recruit Count: 58

Registration Number: NCT01482559

Locations: 🇨🇦
Centre hospitalier universitaire Sainte-Justine, Montreal, Quebec, Canada
🇬🇧
Royal Maternity Hospital, Belfast, United Kingdom
🇮🇪
Royal College of Surgeons in Ireland, Dublin, Ireland

and more 7 locations