Dopamine

Generic Name: Dopamine

Drug Type: Small Molecule

Chemical Formula: C_₈H_₁₁NO_₂

CAS Number: 51-61-6

Unique Ingredient Identifier: VTD58H1Z2X

Background: One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.

Indication: For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure

Associated Conditions: Arrhythmia, Circulatory collapse and shock, Hypotension caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Urine flow decreased caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Decreased cardiac output caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction

Clinical Trials

AZD3427 Effects on Renal Perfusion in Heart Failure Patients With Reduced Ejection Fraction and Renal Impairment

Phase 1

Recruiting

Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF)
Renal Impairment

Interventions: Biological: AZD3427
Other: AZD3427 Placebo
Other: Radiolabelled ligand
Drug: Dopamine
Other: Saline

First Posted Date: 2024-09-25

Last Posted Date: 2025-05-13

Lead Sponsor: AstraZeneca

Target Recruit Count: 12

Registration Number: NCT06611423

Locations: 🇸🇪
Research Site, Solna, Sweden

Exercise Training Versus Ropinirole in Treating Restless Legs Syndrome Among Hemodialysis Patients

Not Applicable

Completed

Conditions: Hemodialysis
Restless Legs Syndrome
ESRD (End Stage Renal Disease)
Diabetes Complications

Interventions: Other: Excercise training
Drug: Dopamine Agonist (Ropinirole)

First Posted Date: 2024-06-21

Last Posted Date: 2024-06-21

Lead Sponsor: Lahore General Hospital

Target Recruit Count: 84

Registration Number: NCT06468371

Locations: 🇵🇰
Lahore General Hospital, Lahore, Lahore, Punjab, Pakistan

Fractional Flow Reserve-guided Stenting Versus Medical Therapy in Atherosclerosis Renal Artery Stenosis

Not Applicable

Recruiting

Conditions: Secondary Hypertension Renal Arterial
Renal Artery Stenosis Atherosclerotic

Interventions: Drug: Dopamine
Diagnostic Test: Fractional Flow Reserve, Renal
Device: Renal artery stenting

First Posted Date: 2024-06-07

Last Posted Date: 2024-08-16

Lead Sponsor: Peking University First Hospital

Target Recruit Count: 200

Registration Number: NCT06447740

Locations: 🇨🇳
Peking University First Hospital, Beijing, Beijing, China

Fractional Flow Reserve to Determine Atherosclerosis Renovascular Hypertension Stenting

Not Applicable

Recruiting

Conditions: Renal Artery Stenosis Atherosclerotic
Secondary Hypertension Renal Arterial

Interventions: Drug: Dopamine
Diagnostic Test: Fractional Flow Reserve, Renal
Device: Renal artery stenting

First Posted Date: 2023-02-16

Last Posted Date: 2024-06-06

Lead Sponsor: Peking University First Hospital

Target Recruit Count: 100

Registration Number: NCT05732077

Locations: 🇨🇳
Peking University First Hospital, Beijing, Beijing, China
🇨🇳
Beijing Anzhen Hospital, Capital Medical University, Beijing, Beijing, China
🇨🇳
The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

and more 10 locations

Prospective Multicenter Cohort Study Evaluating the Incidence and Risk Factors for Problem Gambling Among Young Adults With First-episode Psychosis

Recruiting

Conditions: Gambling Disorder
Psychotic Disorders

Interventions: Drug: Dopamine partial agonists
Other: Psychiatric comorbidities
Other: Sex
Other: Gender
Other: Socioeconomic status
Other: Gambling history

First Posted Date: 2023-01-17

Last Posted Date: 2023-01-18

Lead Sponsor: Laval University

Target Recruit Count: 800

Registration Number: NCT05686772

Locations: 🇨🇦
Montreal University Hospital Center, Montreal, Quebec, Canada
🇨🇦
Quebec Mental Health University Institute, Quebec, Canada

Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis

Recruiting

Conditions: Late-Onset Neonatal Sepsis
Neonatal Hypotension
Extreme Prematurity

Interventions: Drug: Dopamine
Drug: Norepinephrine

First Posted Date: 2022-04-26

Last Posted Date: 2024-11-08

Lead Sponsor: Mount Sinai Hospital, Canada

Target Recruit Count: 550

Registration Number: NCT05347238

Locations: 🇺🇸
Banner-University Medical Center Phoenix, Phoenix, Arizona, United States
🇺🇸
Dayton Children's Hospital, Dayton, Ohio, United States
🇺🇸
El Paso Children's Hospital, El Paso, Texas, United States

and more 23 locations

Respiratory Effects of Dopamine in the Perioperative Care

Not Applicable

Conditions: Dopamine
Bronchodilation
Heart
Surgery
Functional Disturbance

Interventions: Drug: Dopamine administration

First Posted Date: 2021-02-12

Last Posted Date: 2021-02-12

Lead Sponsor: Szeged University

Target Recruit Count: 100

Registration Number: NCT04753008

Locations: 🇭🇺
Barna Babik, Szeged, Hungary

Dopamine Versus Norepinephrine Under General Anesthesia

Phase 3

Completed

Conditions: Congenital Heart Disease
Infant
Hemodynamic Instability
Anesthesia

Interventions: Drug: norepinephrine
Drug: dopamine

First Posted Date: 2020-09-02

Last Posted Date: 2021-10-22

Lead Sponsor: Children's Hospital of Fudan University

Target Recruit Count: 60

Registration Number: NCT04536194

Locations: 🇨🇳
Children's Hospital of Fudan University, Shanghai, Shanghai, China

Dopamine in Neonate

Phase 2

Conditions: Neonates and Preterm Infants

Interventions: Drug: Dopamine

First Posted Date: 2020-08-25

Last Posted Date: 2020-08-25

Lead Sponsor: Seoul National University Hospital

Target Recruit Count: 30

Registration Number: NCT04525495

Locations: 🇰🇷
Seoul National University Children's Hospital, Seoul, Korea, Republic of

PRolaCT - Three Prolactinoma RCTs

Phase 4

Recruiting

Conditions: Prolactinoma
Prolactin-Producing Pituitary Tumor

Interventions: Procedure: Endoscopic trans-sphenoidal adenoma resection
Drug: Dopamine Agonists

First Posted Date: 2019-09-27

Last Posted Date: 2020-07-20

Lead Sponsor: Leiden University Medical Center

Target Recruit Count: 880

Registration Number: NCT04107480

Locations: 🇳🇱
Amsterdam University Medical Center, loc. AMC, Amsterdam-Zuidoost, Noord-Holland, Netherlands
🇳🇱
Reinier de Graaf Gasthuis, Delft, Zuid-Holland, Netherlands
🇳🇱
Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands

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