Omeprazole
- Generic Name
- Omeprazole
- Brand Names
- Konvomep, Losec, Omeclamox, Omesec, Previdolrx Analgesic Pak, Prilosec, Talicia, Yosprala, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19N3O3S
- CAS Number
- 73590-58-6
- Unique Ingredient Identifier
- KG60484QX9
- Background
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class, and its approva...
- Indication
Omeprazole, according to the FDA label is a proton pump inhibitor (PPI) used for the following purposes:
• Treatment of active duodenal ulcer in adults
• Eradication of Helicobacter pylori to reduce the risk of duodenal ulcer
recurrence in adults
• Treatment of active benign gastric ulcer in adults
...
- Associated Conditions
- Ankylosing Spondylitis (AS), Duodenal Ulcer, Erosive Esophagitis, Gastric Ulcer, Gastro-esophageal Reflux Disease (GERD), Healing, Heartburn, Helicobacter Pylori Infection, Osteoarthritis (OA), Rheumatoid Arthritis, Upper GI Bleeding, Zollinger-Ellison Syndrome, Benign, active Gastric Ulcer, Develop NSAID-induced gastric ulcers, Hypersecretory conditions, Multiple endocrine adenomas
- Associated Therapies
- -
A Study to Investigate the Pharmacodynamic Effect After Four-week Omeprazole Treatment of Non-erosive Reflux Disease in a Japanese Population
- Conditions
- First Posted Date
- 2005-11-29
- Last Posted Date
- 2011-01-24
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 40
- Registration Number
- NCT00259051
- Locations
- 🇯🇵
Research Site, Yamato, Japan
Sopran - Omeprazole Treatment Versus Surgery
- Conditions
- First Posted Date
- 2005-11-22
- Last Posted Date
- 2011-01-24
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 219
- Registration Number
- NCT00256737
- Locations
- 🇸🇪
Research Site, Örebro, Sweden
Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer
- First Posted Date
- 2005-11-01
- Last Posted Date
- 2015-04-03
- Lead Sponsor
- Keio University
- Registration Number
- NCT00247130
- Locations
- 🇯🇵
Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer
- Conditions
- Interventions
- First Posted Date
- 2005-09-21
- Last Posted Date
- 2020-12-11
- Lead Sponsor
- Brooklyn ImmunoTherapeutics, LLC
- Target Recruit Count
- 27
- Registration Number
- NCT00210470
Administration of High-Dose Intravenous Proton Pump Inhibitor for Upper Gastrointestinal Bleeding Prior to Endoscopy
- Conditions
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2007-06-06
- Lead Sponsor
- Chinese University of Hong Kong
- Target Recruit Count
- 638
- Registration Number
- NCT00164866
- Locations
- 🇨🇳
Endoscopy Center, Prince of Wales Hospital, Hong Kong SAR, China
Antibiotic Therapy in Treating Patients With Low Grade Gastric Lymphoma
- Conditions
- First Posted Date
- 2004-08-24
- Last Posted Date
- 2012-07-02
- Target Recruit Count
- 96
- Registration Number
- NCT00003151
- Locations
- 🇬🇧
Clatterbridge Centre for Oncology NHS Trust, Merseyside, England, United Kingdom
🇬🇧Royal United Hospital, Bath, England, United Kingdom
🇬🇧Royal Free Hospital, Hampstead, London, England, United Kingdom
Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach
- Conditions
- Interventions
- First Posted Date
- 2004-06-10
- Last Posted Date
- 2018-10-24
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 5
- Registration Number
- NCT00002682
- Locations
- 🇺🇸
University of Texas - MD Anderson Cancer Center, Houston, Texas, United States
🇺🇸MD Anderson Cancer Center Orlando, Orlando, Florida, United States
Chlorambucil Compared With No Further Therapy Following Anti-Helicobacter Therapy in Treating Patients With Low-Grade Lymphoma of the Stomach
- Conditions
- First Posted Date
- 2004-03-12
- Last Posted Date
- 2013-09-20
- Lead Sponsor
- Lymphoma Trials Office
- Target Recruit Count
- 200
- Registration Number
- NCT00003617
- Locations
- 🇬🇧
Clatterbridge Centre for Oncology NHS Trust, Merseyside, England, United Kingdom
🇬🇧Leeds Teaching Hospital Trust, Leeds, England, United Kingdom
🇬🇧Essex County Hospital, Colchester, England, United Kingdom
The Use of Oral Omeprazole and Intravenous Pantoprazole in Patients With Hypersecretion of Gastric Acid
- Conditions
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.