Pentamidine
- Generic Name
- Pentamidine
- Brand Names
- Nebupent, Pentam
- Drug Type
- Small Molecule
- Chemical Formula
- C19H24N4O2
- CAS Number
- 100-33-4
- Unique Ingredient Identifier
- 673LC5J4LQ
- Background
Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
- Indication
For the treatment of pneumonia due to Pneumocystis carinii.
- Associated Conditions
- Pneumocystis Jirovecii Pneumonia, Trypanosomiasis
The Safety and Effectiveness of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Who Have Had PCP Before
- Conditions
- Pneumonia, Pneumocystis CariniiHIV Infections
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Fisons
- Registration Number
- NCT00002291
- Locations
- 🇺🇸
Fisons Corp, Rochester, New York, United States
A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or Sulfonamides
- Conditions
- Pneumonia, Pneumocystis CariniiHIV Infections
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 400
- Registration Number
- NCT00001028
- Locations
- 🇺🇸
Community Consortium of San Francisco, San Francisco, California, United States
🇺🇸Denver CPCRA / Denver Public Hlth, Denver, Colorado, United States
🇺🇸Wilmington Hosp / Med Ctr of Delaware, Wilmington, Delaware, United States
A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDS
- Conditions
- Pneumonia, Pneumocystis CariniiHIV Infections
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-03
- Target Recruit Count
- 240
- Registration Number
- NCT00000715
- Locations
- 🇺🇸
Harvard (Massachusetts Gen Hosp), Boston, Massachusetts, United States
🇺🇸Julio Arroyo, West Columbia, South Carolina, United States
🇺🇸Bronx Municipal Hosp Ctr/Jacobi Med Ctr, Bronx, New York, United States
A Study of Two Forms of Pentamidine in HIV-Infected Children Who May Have Pneumocystis Carinii Pneumonia
- Conditions
- Pneumonia, Pneumocystis CariniiHIV Infections
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 16
- Registration Number
- NCT00000974
- Locations
- 🇺🇸
UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CRS, Los Angeles, California, United States
🇺🇸Childrens Hosp. LA - Dept. of Ped., Div. of Clinical Immunology & Allergy, Los Angeles, California, United States
🇺🇸Children's Hosp. & Research Ctr. Oakland, Ped. Clinical Research Ctr. & Research Lab., Oakland, California, United States
Drug Development Updates
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