Pentamidine
- Generic Name
- Pentamidine
- Brand Names
- Nebupent, Pentam
- Drug Type
- Small Molecule
- Chemical Formula
- C19H24N4O2
- CAS Number
- 100-33-4
- Unique Ingredient Identifier
- 673LC5J4LQ
- Background
Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
- Indication
For the treatment of pneumonia due to Pneumocystis carinii.
- Associated Conditions
- Pneumocystis Jirovecii Pneumonia, Trypanosomiasis
0794GCC: Pentamidine in Treating Patients With Relapsed or Refractory Melanoma
- First Posted Date
- 2008-08-08
- Last Posted Date
- 2019-08-16
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 6
- Registration Number
- NCT00729807
- Locations
- 🇺🇸
Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore, Maryland, United States
Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma
- Conditions
- Lymphoma
- Interventions
- Biological: Bleomycin SulfateBiological: FilgrastimDrug: Trimethoprim-SulfamethoxazoleRadiation: Radiation Therapy
- First Posted Date
- 2004-10-05
- Last Posted Date
- 2012-07-30
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 46
- Registration Number
- NCT00002524
- Locations
- 🇺🇸
MD Anderson Cancer Center Orlando, Orlando, Florida, United States
🇺🇸University of Texas - MD Anderson Cancer Center, Houston, Texas, United States
Combination Immunosuppressive Therapy to Prevent Kidney Transplant Rejection in Adults
- Conditions
- Kidney TransplantationKidney Disease
- Interventions
- First Posted Date
- 2004-03-02
- Last Posted Date
- 2018-06-29
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 10
- Registration Number
- NCT00078559
- Locations
- 🇺🇸
University of Wisconsin - Department of Medicine, Madison, Wisconsin, United States
A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMX
- Conditions
- Pneumonia, Pneumocystis CariniiHIV Infections
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Glaxo Wellcome
- Target Recruit Count
- 615
- Registration Number
- NCT00002340
- Locations
- 🇺🇸
Holmes Hosp, Cincinnati, Ohio, United States
🇺🇸Hampton Roads Med Specialists, Hampton, Virginia, United States
🇺🇸Bay Area AIDS Consortium, Tampa, Florida, United States
Aerosols in the Treatment of Asymptomatic Pneumocystis Pneumonia: A Pilot Study Assessing the Effectiveness of Aerosolized Pentamidine as Treatment of Subclinical Pneumocystis Infection in Patients With No Clinical Symptoms
- Conditions
- Pneumonia, Pneumocystis CariniiHIV Infections
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-02
- Target Recruit Count
- 20
- Registration Number
- NCT00000707
- Locations
- 🇺🇸
SUNY - Stony Brook, Stony Brook, New York, United States
Islet Transplantation for Type 1 Diabetes
- Conditions
- Diabetes Mellitus, Insulin-Dependent
- Interventions
- Procedure: Islet Transplantation
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2017-03-15
- Target Recruit Count
- 36
- Registration Number
- NCT00014911
- Locations
- 🇩🇪
Justus-Leibig University, Giessen, Germany
🇨🇦University of Alberta, Edmonton, Alberta, Canada
🇨ðŸ‡University of Geneva, Geneva, Switzerland
A Study of Two Forms of Pentamidine in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS
- Conditions
- Pneumonia, Pneumocystis CariniiHIV Infections
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- LyphoMed
- Registration Number
- NCT00002292
- Locations
- 🇺🇸
LyphoMed Inc, Rosemont, Illinois, United States
A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients
- Conditions
- HIV InfectionsPneumonia, Pneumocystis Carinii
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-04
- Target Recruit Count
- 600
- Registration Number
- NCT00000991
- Locations
- 🇺🇸
Chicago Children's CRS, Chicago, Illinois, United States
🇺🇸Johns Hopkins Adult AIDS CRS, Baltimore, Maryland, United States
🇺🇸Case CRS, Cleveland, Ohio, United States
A Study of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia
- Conditions
- HIV InfectionsPneumonia, Pneumocystis Carinii
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-04
- Target Recruit Count
- 20
- Registration Number
- NCT00001003
- Locations
- 🇺🇸
SUNY - Stony Brook, Stony Brook, New York, United States
A Study of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Children Who Cannot Take Trimethoprim-Sulfamethoxazole
- Conditions
- Pneumonia, Pneumocystis CariniiHIV Infections
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 32
- Registration Number
- NCT00001027
- Locations
- 🇺🇸
Usc La Nichd Crs, Los Angeles, California, United States
🇺🇸Chicago Children's CRS, Chicago, Illinois, United States
🇺🇸UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CRS, Los Angeles, California, United States
Drug Development Updates
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