Atosiban
- Generic Name
- Atosiban
- Brand Names
- Tractocile, Atosiban SUN
- Drug Type
- Small Molecule
- Chemical Formula
- C43H67N11O12S2
- CAS Number
- 90779-69-4
- Unique Ingredient Identifier
- 081D12SI0Z
- Background
Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used intravenously to halt premature labor. Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form. Atobisan was developed by the Swedish company Ferring Pharmaceuticals. It was first reported in t...
- Indication
Atosiban is indicated for use in delaying imminent pre-term birth in pregnant adult women with:
- Associated Conditions
- Premature Births
- Associated Therapies
- -
A Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm Labour
- Conditions
- Interventions
- First Posted Date
- 2014-11-17
- Last Posted Date
- 2020-07-29
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 97
- Registration Number
- NCT02292771
- Locations
- 🇬🇧
GSK Investigational Site, Sheffield, United Kingdom
Oxytocin Antagonist in Patients With Repeated Failure of Implantation
- First Posted Date
- 2012-08-28
- Last Posted Date
- 2021-02-02
- Lead Sponsor
- AZ Jan Palfijn Gent
- Target Recruit Count
- 138
- Registration Number
- NCT01673399
- Locations
- 🇧🇪
AZ Jan Palfijn, Gent, Oost-vlaanderen, Belgium
Use of Atosiban in in Vitro Fertilization (IVF) Treatment
- First Posted Date
- 2011-12-29
- Last Posted Date
- 2014-01-07
- Lead Sponsor
- The University of Hong Kong
- Target Recruit Count
- 800
- Registration Number
- NCT01501214
- Locations
- 🇻🇳
CGRH, School of Medicine, Ho Chi Minh City, Vietnam
🇨🇳Reproductive Medical Center of Nanfang Hospital, Guangzhou, Guangdong, China
Atosiban Improves Implantation and Pregnancy Rates in Patients With Repeated Implantation Failure
- First Posted Date
- 2011-12-16
- Last Posted Date
- 2011-12-20
- Lead Sponsor
- An Sinh Hospital
- Target Recruit Count
- 71
- Registration Number
- NCT01493440
- Locations
- 🇻🇳
IVFAS, An Sinh Hospital, Ho Chi Minh City, Ho Chi Minh, Vietnam
Single Versus Combination Therapy in Acute Tocolysis
- First Posted Date
- 2011-09-07
- Last Posted Date
- 2011-09-07
- Lead Sponsor
- Tawam Hospital
- Target Recruit Count
- 110
- Registration Number
- NCT01429545
- Locations
- 🇦🇪
Department of obstetrics and Gynecology, Tawam Hospital, Al Ain, Abudhabi, United Arab Emirates
🇦🇪Tawam Hospital, Al Ain, Abudhabi, United Arab Emirates
Nifedipine Treatment in Preterm Labor
- First Posted Date
- 2011-03-15
- Last Posted Date
- 2014-07-29
- Lead Sponsor
- Hospital Clinico Universitario de Santiago
- Registration Number
- NCT01314859
Influence of Tocolytical Medications on Hemodynamics (Central and Peripheral) and Vascular Function in a Pilot Study to Determine the Design of the Final Study and the Final Study Itself
- First Posted Date
- 2008-05-19
- Last Posted Date
- 2009-04-20
- Lead Sponsor
- University Hospital, Ghent
- Target Recruit Count
- 23
- Registration Number
- NCT00679705
- Locations
- 🇧🇪
University Hospital Ghent, Ghent, Belgium
Nifedipine Compared to Atosiban for Treating Preterm Labor
- First Posted Date
- 2008-01-24
- Last Posted Date
- 2012-03-13
- Lead Sponsor
- Raed Salim
- Target Recruit Count
- 145
- Registration Number
- NCT00599898
- Locations
- 🇮🇱
HaEmek Medical Center, Afula, Israel
Effect of Oxytocin and Vasopressin Antagonists on Uterine Contractions
- Conditions
- Interventions
- First Posted Date
- 2008-01-07
- Last Posted Date
- 2017-06-21
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 125
- Registration Number
- NCT00587327
- Locations
- 🇪🇸
Institut Universitari Dexeus, Barcelona, Spain
🇪🇸IVI Madrid, Madrid, Spain
🇨🇿Institute for Reproductive Medicine and Endocrinology, Pilsen, Czechia
Drug Development Updates
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