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Permethrin

Generic Name
Permethrin
Brand Names
Elimite, Nix Cream Rinse
Drug Type
Small Molecule
Chemical Formula
C21H20Cl2O3
CAS Number
52645-53-1
Unique Ingredient Identifier
509F88P9SZ
Background

A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.

Indication

For the treatment of infestation with Sarcoptes scabiei (scabies).

Associated Conditions
Head Lice Infestation, Norwegian scabies, Scabies, Lice of the pubic area

A Bioequivalence Study With Clinical Endpoints to Evaluate the Safety and Therapeutic Equivalence of Permethrin Cream 5% & Elimite™ in Subjects With Scabies

Phase 3
Completed
Conditions
Scabies
Interventions
First Posted Date
2019-06-04
Last Posted Date
2020-10-23
Lead Sponsor
Saptalis Pharmaceuticals LLC
Target Recruit Count
126
Registration Number
NCT03973775
Locations
🇺🇸

Havana Research Institute, Pasadena, California, United States

🇺🇸

Universal Biopharma Research Institute Inc., Dinuba, California, United States

🇺🇸

SouthCoast Research Center, Inc (Clinical Site & Drug Shipment Facility), Miami, Florida, United States

and more 2 locations

Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands

Phase 3
Completed
Conditions
Scabies
Head Lice
Interventions
First Posted Date
2017-08-01
Last Posted Date
2019-06-14
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
118
Registration Number
NCT03236168
Locations
🇸🇧

Atoifi Adventist Hospital, Atoifi, Malaita, Solomon Islands

Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% in the Treatment of Scabies

Phase 3
Completed
Conditions
Scabies
Interventions
Drug: Elimite™ Cream (permethrin) 5%
First Posted Date
2017-06-07
Last Posted Date
2019-03-26
Lead Sponsor
Encube Ethicals Pvt. Ltd.
Target Recruit Count
254
Registration Number
NCT03178942
Locations
🇺🇸

Applied Research Center of Arkansas, Little Rock, Arkansas, United States

🇺🇸

Lenus Research & Medical Group, LLC, Sweetwater, Florida, United States

🇸🇻

Clinica Dermatologica/APF Research International, San Salvador, El Salvador

and more 11 locations

The Efficacy of Permethrin 5%, Fusidic Acid 1% and Synthomycine 5% for Demodex - Blepharitis

Phase 4
Conditions
Inflammation of the Eyelids
Interventions
Drug: Synthomycine 5%
Drug: Fusidic Acid 1% M/R Eye Drops
First Posted Date
2017-04-10
Last Posted Date
2018-01-30
Lead Sponsor
Barzilai Medical Center
Target Recruit Count
75
Registration Number
NCT03105505
Locations
🇮🇱

Barzilai Medical Center, Ashqelon, Israel

Bio-equivalence Study Comparing Permethrin Cream, 5% With Elimite in Patients With Active Scabies.

Phase 3
Completed
Conditions
Scabies
Interventions
First Posted Date
2016-12-01
Last Posted Date
2020-09-02
Lead Sponsor
Mayne Pharma International Pty Ltd
Target Recruit Count
140
Registration Number
NCT02978508
Locations
🇺🇸

Southcoast Research Center, Miami, Florida, United States

🇺🇸

LCC Medical Research Institute, Miami, Florida, United States

🇺🇸

Mid Columbia Research, Richland, Washington, United States

Azithromycin - Ivermectin Mass Drug Administration for Skin Disease

Phase 4
Completed
Conditions
Yaws
Impetigo
Scabies
Interventions
First Posted Date
2016-05-17
Last Posted Date
2019-09-17
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
1291
Registration Number
NCT02775617
Locations
🇸🇧

Atoifi Adventist Hospital, Atoifi, Malaita, Solomon Islands

Malaria Elimination Pilot Study in Military Forces in Cambodia

Phase 4
Conditions
Malaria
Parasitic Diseases
Interventions
First Posted Date
2016-01-13
Last Posted Date
2021-03-02
Lead Sponsor
Armed Forces Research Institute of Medical Sciences, Thailand
Target Recruit Count
1050
Registration Number
NCT02653898
Locations
🇰🇭

RCAF treatment facilities, Anlong Veng, Oddar Meancheay, Cambodia

A Study to Evaluate the Therapeutic Equivalence of Generic Permethrin Cream 5% to Elimite® in the Treatment of Scabies

Phase 3
Completed
Conditions
Scabies
Interventions
First Posted Date
2015-10-09
Last Posted Date
2016-10-14
Lead Sponsor
Dr. Reddy's Laboratories Limited
Target Recruit Count
250
Registration Number
NCT02572986
Locations
🇺🇸

Sun Research Institute, San Antonio, Texas, United States

🇺🇸

Zain Research, LLC, Richland, Washington, United States

🇺🇸

Derm Dx Center for Dermatology, Hazleton, Pennsylvania, United States

and more 10 locations

Cocamide DEA vs Permethrin for Head Lice

Phase 3
Terminated
Conditions
Pediculosis Capitis
Head Louse Infestation
Interventions
Drug: Cocamide diethanolamine
First Posted Date
2015-07-16
Last Posted Date
2015-07-16
Lead Sponsor
Medical Entomology Centre
Target Recruit Count
44
Registration Number
NCT02500524
Locations
🇬🇧

Medical Entomology Centre, Cambridge, United Kingdom

Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children and Adults

Phase 3
Completed
Conditions
Scabies
Interventions
First Posted Date
2015-04-03
Last Posted Date
2024-06-17
Lead Sponsor
University Hospital, Bordeaux
Target Recruit Count
1092
Registration Number
NCT02407782
Locations
🇫🇷

CHU de Dijon, Dijon, Bourgogne, France

🇫🇷

CHG de Chalon sur Saône, Chalon sur Saône, Bourgogne, France

🇫🇷

CHU de Rennes, Rennes, Bretagne, France

and more 26 locations
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