DeepMed Research

Nitrite

Generic Name: Nitrite

Drug Type: Small Molecule

Chemical Formula: NO_₂

CAS Number: 14797-65-0

Unique Ingredient Identifier: J39976L608

Background: Nitrite is under investigation for the treatment of Heart Failure.

Clinical Trials

Nitrites in Acute Myocardial Infarction

Phase 2

Completed

Conditions: Acute ST Elevation Myocardial Infarction

Interventions: Drug: sodium nitrite
Other: Placebo

First Posted Date: 2011-07-06

Last Posted Date: 2016-01-21

Lead Sponsor: University of Aberdeen

Target Recruit Count: 200

Registration Number: NCT01388504

Locations: 🇬🇧
Aberdeen Royal Infirmary, Aberdeen, United Kingdom
🇬🇧
Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom
🇬🇧
St George's Healthcare NHS Trust, London, United Kingdom

Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders

Phase 1

Completed

Conditions: Sickle Cell Disease
Chronic Hemolytic Disorders
Sickle Cell Anemia

First Posted Date: 2011-03-16

Last Posted Date: 2018-10-22

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 28

Registration Number: NCT01316796

Locations: 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Pilot Study of Sodium Nitrite in Resuscitated Cardiac Arrest Patients

Phase 1

Completed

Conditions: Cardiac Arrest

First Posted Date: 2010-08-10

Last Posted Date: 2017-05-18

Lead Sponsor: University of Washington

Target Recruit Count: 11

Registration Number: NCT01178359

Locations: 🇺🇸
Harborview Medical Center, Seattle, Washington, United States

Nitrite Mediated Cardioprotection During Coronary Artery Bypass Surgery

Phase 2

Conditions: Coronary Artery Bypass Surgery

Interventions: Drug: sodium nitrite
Drug: 0.9% sodium chloride

First Posted Date: 2010-04-02

Last Posted Date: 2010-04-02

Lead Sponsor: University Hospital Birmingham NHS Foundation Trust

Target Recruit Count: 50

Registration Number: NCT01098409

Locations: 🇬🇧
University Hospitals Birmingham NHS Trust, Birmingham, United Kingdom

Sodium Nitrite in Acute Myocardial Infarction

Phase 2

Completed

Conditions: Acute Myocardial Infarction

Interventions: Drug: Sodium Nitrite

First Posted Date: 2009-06-18

Last Posted Date: 2018-05-14

Lead Sponsor: Johns Hopkins University

Target Recruit Count: 30

Registration Number: NCT00924118

Locations: 🇺🇸
Johns Hopkins Bayview Medical Center, Baltimore, Maryland, United States
🇺🇸
Johns Hopkins Hospital, Baltimore, Maryland, United States
🇺🇸
University of Massachusetts Medical School, Worcester, Massachusetts, United States

Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm

Phase 2

Completed

Conditions: Subarachnoid Hemorrhage

Interventions: Drug: Saline
Drug: Sodium nitrite

First Posted Date: 2009-04-01

Last Posted Date: 2020-05-21

Lead Sponsor: Hope Pharmaceuticals

Target Recruit Count: 19

Registration Number: NCT00873015

Locations: 🇺🇸
University of Virginia Health System Medical Center, Charlottesville, Virginia, United States

Dose-Finding, Safety, Pharmacodynamic Effect Study of Sodium Nitrite Inhalation Solution in Normal, Healthy Volunteers

Phase 1

Completed

Conditions: Pulmonary Arterial Hypertension

Interventions: Drug: Sodium Nitrite Inhalation Solution
Drug: Placebo and AIR001 Inhalation Solution (Expansion arm)

First Posted Date: 2008-12-25

Last Posted Date: 2012-02-17

Lead Sponsor: Aires Pharmaceuticals, Inc.

Target Recruit Count: 25

Registration Number: NCT00814645

Locations: 🇺🇸
DaVita Clinical Research, Minneapolis, Minnesota, United States

Effect of Nitrite on Exercise Physiology and Metabolism

Phase 1

Terminated

Conditions: Healthy Volunteer
Healthy
HV

First Posted Date: 2005-03-10

Last Posted Date: 2018-07-05

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 15

Registration Number: NCT00105222

Locations: 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Nitrite Infusion in Healthy Volunteers

Phase 1

Completed

Conditions: Healthy

First Posted Date: 2005-02-07

Last Posted Date: 2017-07-02

Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Target Recruit Count: 12

Registration Number: NCT00103025

Locations: 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Nitrite Infusion Studies

Phase 1

Completed

Conditions: Healthy

First Posted Date: 2005-01-26

Last Posted Date: 2017-07-02

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 36

Registration Number: NCT00102271

Locations: 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2025. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy