Nitrite
- Generic Name
- Nitrite
- Drug Type
- Small Molecule
- Chemical Formula
- NO2
- CAS Number
- 14797-65-0
- Unique Ingredient Identifier
- J39976L608
- Background
Nitrite is under investigation for the treatment of Heart Failure.
Haemodynamic Effects of Dobutamine and Nitrite in LV Dysfunction
- Conditions
- Heart Failure
- First Posted Date
- 2016-09-05
- Last Posted Date
- 2016-09-05
- Lead Sponsor
- King's College London
- Target Recruit Count
- 45
- Registration Number
- NCT02888561
- Locations
- π¬π§
British Heart Foundation Centre of Excellence, The Rayne Institute, KCL, at Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers
- Conditions
- Sickle Cell Disease
- Interventions
- Other: Placebo
- First Posted Date
- 2016-08-11
- Last Posted Date
- 2025-05-07
- Lead Sponsor
- caterina P minniti
- Target Recruit Count
- 18
- Registration Number
- NCT02863068
- Locations
- πΊπΈ
Montefiore Medical Center - Albert Einstein College of Medicine, Bronx, New York, United States
πΊπΈDuke University Medical Center, Durham, North Carolina, United States
πΊπΈUniversity of Pittsburgh, Pittsburgh, Pennsylvania, United States
Inorganic Nitrite Delivery to Improve Exercise Capacity in HFpEF
- First Posted Date
- 2016-04-18
- Last Posted Date
- 2019-03-13
- Lead Sponsor
- Adrian Hernandez
- Target Recruit Count
- 105
- Registration Number
- NCT02742129
- Locations
- πΊπΈ
Massachusetts General Hospital, Boston, Massachusetts, United States
πΊπΈJefferson Medical College, Philadelphia, Pennsylvania, United States
πΊπΈThe University of Vermont - Fletcher Allen Health Care, Burlington, Vermont, United States
Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction (HFpEF) (INABLE-Training)
- Conditions
- Heart Failure
- Interventions
- First Posted Date
- 2016-03-18
- Last Posted Date
- 2023-04-26
- Lead Sponsor
- Barry Borlaug
- Target Recruit Count
- 92
- Registration Number
- NCT02713126
- Locations
- πΊπΈ
Mayo Clinic, Rochester, Minnesota, United States
Inhaled Sodium Nitrite as an Antimicrobial for Cystic Fibrosis
- First Posted Date
- 2016-02-29
- Last Posted Date
- 2024-06-24
- Lead Sponsor
- Schmidhofer, Mark, MD
- Target Recruit Count
- 4
- Registration Number
- NCT02694393
- Locations
- πΊπΈ
Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States
πΊπΈComprehensive Lung Center - Falk Clinic, Pittsburgh, Pennsylvania, United States
The Effect of Sodium Nitrite on Renal Function and Blood Pressure in Hypertensive Versus Healthy Subjects
- First Posted Date
- 2015-08-19
- Last Posted Date
- 2015-08-19
- Lead Sponsor
- Erling Bjerregaard Pedersen
- Target Recruit Count
- 30
- Registration Number
- NCT02527837
- Locations
- π©π°
Department of Medical Research and Medicine, Holstebro Regional Hospital, Holstebro, Denmark
Three New Ideas to Protect Special Forces From the Stress of High Altitude
- Conditions
- Mountain Sickness
- Interventions
- Dietary Supplement: QuercetinDrug: Placebo
- First Posted Date
- 2015-06-04
- Last Posted Date
- 2021-03-30
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 148
- Registration Number
- NCT02463357
- Locations
- πΊπΈ
Alma College, Alma, Michigan, United States
The Effects of NOx and Conjugated Linoleic Acid on Asthmatics
- Conditions
- Asthma
- Interventions
- First Posted Date
- 2015-05-05
- Last Posted Date
- 2021-04-27
- Lead Sponsor
- Gladwin, Mark, MD
- Target Recruit Count
- 6
- Registration Number
- NCT02433977
- Locations
- πΊπΈ
The University of Pittsburgh Asthma Institute at UPMC, Pittsburgh, Pennsylvania, United States
A Phase 2a Study to Assess Safety & Pharmacokinetics of Sustained Release Sodium Nitrite in Patients With Diabetic Pain
- First Posted Date
- 2015-04-09
- Last Posted Date
- 2020-04-24
- Lead Sponsor
- TheraVasc Inc.
- Target Recruit Count
- 26
- Registration Number
- NCT02412852
- Locations
- πΊπΈ
Ohio Pain Clinic, Centerville, Ohio, United States
Nitrite Supplementation for Improving Physiological Function in Older Adults
- First Posted Date
- 2015-03-19
- Last Posted Date
- 2019-12-05
- Lead Sponsor
- University of Colorado, Boulder
- Target Recruit Count
- 49
- Registration Number
- NCT02393742
- Locations
- πΊπΈ
Clinical Translational Research Center, Boulder, Colorado, United States
Drug Development Updates
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