Furosemide
- Generic Name
- Furosemide
- Brand Names
- Furoscix, Lasix
- Drug Type
- Small Molecule
- Chemical Formula
- C12H11ClN2O5S
- CAS Number
- 54-31-9
- Unique Ingredient Identifier
- 7LXU5N7ZO5
- Background
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrol...
- Indication
Furosemide is indicated for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome, in adults and pediatric patients.
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- Associated Conditions
- Acute Pulmonary Edema, Ascites, Body Fluid Retention, Edema, Hypertension, Mild to Moderate Hypertension, Chest congestion
- Associated Therapies
- -
Safety and Efficacy of Low Dose Hypertonic Saline Solution and High Dose Furosemide for Congestive Heart Failure
- Conditions
- Interventions
- First Posted Date
- 2009-12-09
- Last Posted Date
- 2012-02-09
- Target Recruit Count
- 50
- Registration Number
- NCT01028170
- Locations
- 🇺🇸
Aspirus Wausau Hospital, Wausau, Wisconsin, United States
The Effects of Decreasing the Lasix Dose on the Cardiorenal System
- First Posted Date
- 2009-09-23
- Last Posted Date
- 2015-07-20
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 41
- Registration Number
- NCT00982423
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Furosemide in Early Acute Kidney Injury
- First Posted Date
- 2009-09-16
- Last Posted Date
- 2015-09-30
- Lead Sponsor
- University of Alberta
- Target Recruit Count
- 72
- Registration Number
- NCT00978354
- Locations
- 🇦🇺
Austin Hospital, Melbourne, Victoria, Australia
🇦🇺Princess Alexandra Hospital, Brisbane, Queensland, Australia
🇨🇦University of Laval, Quebec City, Quebec, Canada
Effect of Furosemide on Obesity-induced Glomerular Hyperfiltration
- First Posted Date
- 2009-08-19
- Last Posted Date
- 2011-08-04
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 3
- Registration Number
- NCT00962286
- Locations
- 🇮🇱
Rabin Medical Center, Petach Tikva, Israel
Effect of Diuretics on Fluid Status Control and Residual Renal Function in Peritoneal Dialysis Patients
- First Posted Date
- 2009-07-10
- Last Posted Date
- 2015-05-21
- Lead Sponsor
- Sun Yat-sen University
- Registration Number
- NCT00936923
- Locations
- 🇨🇳
The 1st Affiliated Hospital, Sun Yet-sen University, Guangzhou, Guangdong, China
Dopamine in Acute Decompensated Heart Failure (DAD-HF) Trial
- Conditions
- Interventions
- First Posted Date
- 2009-07-10
- Last Posted Date
- 2010-05-26
- Lead Sponsor
- Larissa University Hospital
- Target Recruit Count
- 300
- Registration Number
- NCT00937092
- Locations
- 🇬🇷
Department of Cardiology, Larissa University Hospital, Larissa, Greece
🇬🇷Department of Cardiology, Volos General Hospital, Volos, Magnesia, Greece
Comparing the Effects of Conivaptan and Diuretics on Plasma Neurohormones and Renal Blood Flow in Patients With Chronic Congestive Heart Failure
- Conditions
- Interventions
- First Posted Date
- 2009-06-18
- Last Posted Date
- 2009-06-18
- Lead Sponsor
- Hennepin County Medical Center, Minneapolis
- Target Recruit Count
- 8
- Registration Number
- NCT00924014
- Locations
- 🇺🇸
Hennepin county Medical Center, Minneapolis, Minnesota, United States
Effect of Repeated Dosing of Naproxcinod on Renal Hemodynamic and on Sodium Balance in Healthy Volunteers Before and After a Single Dose of Furosemide
- Conditions
- Interventions
- First Posted Date
- 2009-05-28
- Last Posted Date
- 2011-06-17
- Lead Sponsor
- NicOx
- Target Recruit Count
- 31
- Registration Number
- NCT00909519
Protocol to Assess the Severity of Acute Kidney Injury
- First Posted Date
- 2008-05-07
- Last Posted Date
- 2022-10-18
- Lead Sponsor
- George Washington University
- Target Recruit Count
- 77
- Registration Number
- NCT00673244
- Locations
- 🇺🇸
George Washington University Hospital, Washington, District of Columbia, United States
A Study To Compare Effects Of GSK189075 In Combination With Either Furosemide Or Hydrochlorothiazide
- Conditions
- First Posted Date
- 2008-05-05
- Last Posted Date
- 2012-03-19
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 48
- Registration Number
- NCT00671424
- Locations
- 🇺🇸
GSK Investigational Site, Columbus, Ohio, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.