Citalopram
- Generic Name
- Citalopram
- Brand Names
- Celexa, Ctp
- Drug Type
- Small Molecule
- Chemical Formula
- C20H21FN2O
- CAS Number
- 59729-33-8
- Unique Ingredient Identifier
- 0DHU5B8D6V
- Background
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. Citalopram enhances serotonergic transmission through the i...
- Indication
Citalopram is approved by the FDA for treating adults with major depressive disorder. It has also been used off-label to treat various diseases, including but not limited to sexual dysfunction, ethanol abuse, psychiatric conditions such as obsessive-compulsive disorder (OCD), social anxiety disorder, panic disorder, and diabetic neuropathy.
- Associated Conditions
- Alcohol Abuse, Anorexia Nervosa (AN), Binge Eating Disorder (BED), Bulimia Nervosa, Depression, Diabetic Neuropathies, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premature Ejaculation, Premenstrual Dysphoric Disorder (PMDD), Separation Anxiety Disorder, Social Anxiety Disorder (SAD)
- Associated Therapies
- -
A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder
- Conditions
- Interventions
- First Posted Date
- 2020-07-17
- Last Posted Date
- 2023-12-22
- Lead Sponsor
- Biogen
- Target Recruit Count
- 440
- Registration Number
- NCT04476030
- Locations
- 🇺🇸
Sage Investigational Site, Bellevue, Washington, United States
Effects of Serotonin Agonist Citalopram on Multimodal Esophageal Stimulation in Healthy Volunteers
- First Posted Date
- 2020-04-21
- Last Posted Date
- 2020-04-21
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Target Recruit Count
- 14
- Registration Number
- NCT04355455
Citalopram and Self Emotional Processing
- First Posted Date
- 2019-11-19
- Last Posted Date
- 2019-11-19
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 44
- Registration Number
- NCT04169230
- Locations
- 🇬🇧
University of Oxford, Oxford, United Kingdom
Citalopram and Stress Reactivity
- Conditions
- Interventions
- First Posted Date
- 2019-11-13
- Last Posted Date
- 2019-11-15
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 40
- Registration Number
- NCT04161209
- Locations
- 🇬🇧
University of Oxford, Oxford, United Kingdom
Brain Response to Serotonergic Medications in ASD
- Conditions
- Interventions
- First Posted Date
- 2019-10-30
- Last Posted Date
- 2022-04-15
- Lead Sponsor
- King's College London
- Target Recruit Count
- 100
- Registration Number
- NCT04145076
- Locations
- 🇬🇧
King's College London, London, United Kingdom
A Clinical Study to Examine the Drug-drug Interactions Between ACT-541468 and Citalopram in Healthy Male and Female Subjects
- Conditions
- Interventions
- First Posted Date
- 2019-04-08
- Last Posted Date
- 2019-10-31
- Lead Sponsor
- Idorsia Pharmaceuticals Ltd.
- Target Recruit Count
- 24
- Registration Number
- NCT03907215
- Locations
- 🇩🇪
Parexel International GmbH, Berlin, Germany
A Study in People With Depression to Test the Effects of BI 1358894 on Parts of the Brain That Are Involved in Emotions
- Conditions
- Interventions
- First Posted Date
- 2019-02-26
- Last Posted Date
- 2021-11-24
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 73
- Registration Number
- NCT03854578
- Locations
- 🇩🇪
Charité - Universitätsmedizin Berlin, Berlin, Germany
Vortioxetine in the Elderly vs. Selective Serotonin Reuptake Inhibitors (SSRIs): a Pragmatic Assessment
- Conditions
- Interventions
- First Posted Date
- 2018-12-19
- Last Posted Date
- 2023-05-19
- Target Recruit Count
- 362
- Registration Number
- NCT03779789
- Locations
- 🇮🇹
Azienda Ospedaliera Universitaria Mater Domini, Università Magna Grecia, Catanzaro, Italy
🇮🇹Sapienza Università di Roma, Dipartimento di Neurologia e Psichiatria, Roma, Italy
🇮🇹Azienda Ospedaliera Universitaria Verona, Verona, Italy
Auricular Concha Electro-acupuncture for the Treatment of Depression
- Conditions
- Interventions
- First Posted Date
- 2018-07-31
- Last Posted Date
- 2019-04-22
- Lead Sponsor
- China Academy of Chinese Medical Sciences
- Target Recruit Count
- 106
- Registration Number
- NCT03607331
- Locations
- 🇨🇳
Institute of Acupuncture and Moxibustion, Beijing, Beijing, China
PF-04995274 and Emotional Processing in Un-medicated Depression
- Conditions
- Interventions
- First Posted Date
- 2018-05-04
- Last Posted Date
- 2022-11-03
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 90
- Registration Number
- NCT03516604
- Locations
- 🇬🇧
University of Oxford, Oxford, Oxfordshire, United Kingdom
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.