Citalopram

Generic Name
Citalopram
Brand Names
Celexa, Ctp
Drug Type
Small Molecule
Chemical Formula
C20H21FN2O
CAS Number
59729-33-8
Unique Ingredient Identifier
0DHU5B8D6V
Background

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. Citalopram enhances serotonergic transmission through the i...

Indication

Citalopram is approved by the FDA for treating adults with major depressive disorder. It has also been used off-label to treat various diseases, including but not limited to sexual dysfunction, ethanol abuse, psychiatric conditions such as obsessive-compulsive disorder (OCD), social anxiety disorder, panic disorder, and diabetic neuropathy.

Associated Conditions
Alcohol Abuse, Anorexia Nervosa (AN), Binge Eating Disorder (BED), Bulimia Nervosa, Depression, Diabetic Neuropathies, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premature Ejaculation, Premenstrual Dysphoric Disorder (PMDD), Separation Anxiety Disorder, Social Anxiety Disorder (SAD)
Associated Therapies
-

Microbiome of Depression & Treatment Response to Citalopram

First Posted Date
2015-01-01
Last Posted Date
2018-03-21
Lead Sponsor
Mayo Clinic
Target Recruit Count
34
Registration Number
NCT02330068
Locations
🇺🇸

Mayo Clinic in Florida, Jacksonville, Florida, United States

🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Serotonin-norepinephrine Reuptake Inhibitors and Acute Kidney Injury

First Posted Date
2014-12-19
Last Posted Date
2016-03-14
Lead Sponsor
Canadian Network for Observational Drug Effect Studies, CNODES
Target Recruit Count
3255526
Registration Number
NCT02320240
Locations
🇨🇦

Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada

A New Treatment Approach for Major Depressive Disorder Based Upon Targeting Monoamine Oxidase A (MAO-A)

First Posted Date
2014-10-21
Last Posted Date
2019-05-24
Lead Sponsor
Centre for Addiction and Mental Health
Target Recruit Count
10
Registration Number
NCT02269540
Locations
🇨🇦

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada

Optimizing Antidepressant Treatment by Genotype-dependent Adjustment of Medication According to the ABCB1 Gene

First Posted Date
2014-09-12
Last Posted Date
2014-09-12
Lead Sponsor
HolsboerMaschmeyer NeuroChemie GmbH
Target Recruit Count
80
Registration Number
NCT02237937
Locations
🇩🇪

Max Planck Institute of Psychiatry, Munich, Bavaria, Germany

Antidepressants and Bone Mineral Density

First Posted Date
2014-07-01
Last Posted Date
2014-07-01
Lead Sponsor
Guiyang Medical University
Target Recruit Count
203
Registration Number
NCT02179268

Mechanism of tDCS-induced Learning Enhancement - the Role of Serotonin

First Posted Date
2014-03-20
Last Posted Date
2021-05-12
Lead Sponsor
Charite University, Berlin, Germany
Target Recruit Count
40
Registration Number
NCT02092974
Locations
🇩🇪

Charite Universitätsmedizin Berlin, Berlin, Germany

Brain Function and Structure in Cocaine Dependence

Phase 2
Completed
Conditions
Interventions
First Posted Date
2014-03-06
Last Posted Date
2017-12-26
Lead Sponsor
Virginia Commonwealth University
Target Recruit Count
54
Registration Number
NCT02080832
Locations
🇺🇸

Virginia Commonwealth University, Richmond, Virginia, United States

The Effects of Vilazodone on Glutamate in the Anterior Cingulate Cortex in Anxious Unipolar Depressives

First Posted Date
2014-01-06
Last Posted Date
2016-11-08
Lead Sponsor
Massachusetts General Hospital
Registration Number
NCT02028026
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Efficacy of Exposure and Response Prevention(ERP) and SSRIs in Chinese OCD Patients

First Posted Date
2013-12-30
Last Posted Date
2022-09-09
Lead Sponsor
Shanghai Mental Health Center
Target Recruit Count
78
Registration Number
NCT02022709
Locations
🇨🇳

Shanghai Mental Health Center, Shanghai, Shanghai, China

Neuroimaging Predictors of Antidepressant Treatment Outcome

First Posted Date
2013-12-04
Last Posted Date
2016-11-21
Lead Sponsor
University of Michigan
Registration Number
NCT02000726
Locations
🇺🇸

Department of Psychiatry, Ann Arbor, Michigan, United States

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