Acetazolamide

Generic Name
Acetazolamide
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C4H6N4O3S2
CAS Number
59-66-5
Unique Ingredient Identifier
O3FX965V0I
Background

One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of...

Indication

For adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies; chronic simple (open-angle) glaucoma

Associated Conditions
Acute angle-closure glaucoma, Edema, Familial periodic paralysis, Generalized Tonic-Clonic Seizures, Metabolic Alkalosis, Open Angle Glaucoma (OAG), Other and unspecified effects of high altitude, Cystine renal calculi, Drug-induced edema, Nonuveitic secondary glaucoma, Salicylate intoxication
Associated Therapies
Urine alkalinization therapy

Predicting Successful Sleep Apnea Treatment With Acetazolamide in Heart Failure Patients

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2011-06-22
Last Posted Date
2018-06-13
Lead Sponsor
David Andrew Wellman
Target Recruit Count
29
Registration Number
NCT01377987
Locations
🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

Intracranial Pressure in Experimental Models of Headache

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2011-02-02
Last Posted Date
2012-02-07
Lead Sponsor
Bangor University
Target Recruit Count
23
Registration Number
NCT01288781
Locations
🇬🇧

School of Sport, Health and Exercise Sciences, Bangor University, Bangor, Gwynedd, United Kingdom

Study of Cobalt's Role in Excessive Erythrocytosis Among High Altitude Dwellers in Cerro de Pasco, Peru

First Posted Date
2010-08-23
Last Posted Date
2015-05-15
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
85
Registration Number
NCT01187108
Locations
🇵🇪

Chronic mountain sickness clinic, Cerro de Pasco, Pasco, Peru

Acetazolamide Facilitates Ventilator Weaning

First Posted Date
2010-05-27
Last Posted Date
2010-05-27
Lead Sponsor
Asan Medical Center
Target Recruit Count
150
Registration Number
NCT01131377
Locations
🇰🇷

AMC MICU; Asan medical center, Seoul, 388-1, Pungnap-dong, Songpa-gu, Korea, Republic of

Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention

First Posted Date
2010-02-02
Last Posted Date
2012-09-10
Lead Sponsor
Sheba Medical Center
Target Recruit Count
55
Registration Number
NCT01060969
Locations
🇮🇱

Center of Geographic Medicine, Tel Hashomer, Israel

🇮🇱

Sheba Medical Ctr., Tel hashomer, Israel

Idiopathic Intracranial Hypertension Treatment Trial

First Posted Date
2009-10-29
Last Posted Date
2018-12-12
Lead Sponsor
St. Luke's-Roosevelt Hospital Center
Target Recruit Count
165
Registration Number
NCT01003639
Locations
🇺🇸

Doheny Eye Center, University of Southern California, Los Angeles, California, United States

🇺🇸

The Eye Care Group, PC, Waterbury, Connecticut, United States

🇺🇸

Neuro-Ophthamology & Balance Disorders Clinic, Tallahassee, Florida, United States

and more 38 locations

Continuous Positive Airway Pressure and Acetazolamide to Treat Sleep Apnea Syndrome Patients at Altitude

First Posted Date
2009-06-26
Last Posted Date
2014-05-20
Lead Sponsor
University of Zurich
Target Recruit Count
51
Registration Number
NCT00928655
Locations
🇨🇭

University Hospital of Zurich, Pulmonary Division and Sleep Disorders Centre, Zurich, Switzerland

Effect of Potassium and Acetazolamide on People With Andersen-Tawil Syndrome

First Posted Date
2009-02-09
Last Posted Date
2012-01-20
Lead Sponsor
University of Rochester
Target Recruit Count
3
Registration Number
NCT00839501
Locations
🇺🇸

University of Rochester School of Medicine, Rochester, New York, United States

Effectiveness of Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis in Intraocular Pressure (IOP) After Bevacizumab

First Posted Date
2008-12-09
Last Posted Date
2008-12-09
Lead Sponsor
University of Sao Paulo
Registration Number
NCT00804921
Locations
🇧🇷

School of Medicine - Clinical Hospital, Ribeirao Preto, SP, Brazil

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