Cefazolin
- Generic Name
- Cefazolin
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C14H14N8O4S3
- CAS Number
- 25953-19-9
- Unique Ingredient Identifier
- IHS69L0Y4T
- Background
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
- Indication
Mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. May be used for surgical prophylax...
- Associated Conditions
- Bacterial Septicemia caused by susceptible Bacterial Infections, Biliary tract infection bacterial caused by susceptible Bacterial Infections, Bone and Joint Infections caused by susceptible Bacterial Infections, Catheter-related Bloodstream Infection (CRBSI) NOS, Community Acquired Pneumonia (CAP), Endocarditis caused by susceptible Bacterial Infections, Genital infection caused by susceptible Bacterial Infections, Osteoarticular Infections, Postoperative Infections, Respiratory Tract Infection Bacterial caused by susceptible Bacterial Infections, Skin and Soft Tissue Infections (SSTIs), Skin and Subcutaneous Tissue Infection caused by susceptible Bacterial Infections, Susceptible infections, Urinary Tract Infection caused by susceptible Bacterial Infections, Perioperative infection, Susceptible Bacterial Infections
- Associated Therapies
- Antibiotic pre-surgical prophylaxis
The Effect of Bowel Preparation on Perioperative Bleeding
- First Posted Date
- 2015-07-10
- Last Posted Date
- 2015-07-10
- Lead Sponsor
- Isfahan University of Medical Sciences
- Target Recruit Count
- 105
- Registration Number
- NCT02493894
- Locations
- 🇮🇷
Alzahra Hospital, Isfahan, Iran, Islamic Republic of
Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy
- First Posted Date
- 2015-05-18
- Last Posted Date
- 2017-01-18
- Target Recruit Count
- 100
- Registration Number
- NCT02446782
- Locations
- 🇮🇳
PGIMER, Chandigarh, India
Preoperative Antibiotic Dosing for Total Knee Arthroplasty
- Conditions
- Interventions
- First Posted Date
- 2015-05-05
- Last Posted Date
- 2017-07-28
- Lead Sponsor
- Duke University
- Registration Number
- NCT02433704
- Locations
- 🇺🇸
Duke Medical Plaza Page Road, Durham, North Carolina, United States
The Influence of Antibiotic Prophylaxis on Intraoperative Prosthetic Joint Infection Cultures
- Conditions
- Interventions
- First Posted Date
- 2015-04-09
- Last Posted Date
- 2016-08-03
- Lead Sponsor
- Parc de Salut Mar
- Target Recruit Count
- 28
- Registration Number
- NCT02413034
Penetration of Cefazolin Into Hepatic Cysts
- Conditions
- Interventions
- First Posted Date
- 2015-02-20
- Last Posted Date
- 2016-02-03
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 8
- Registration Number
- NCT02368015
- Locations
- 🇳🇱
Radboud University Nijmegen Medical Center; Department of Gastroenterology & Hepatology, Nijmegen, Gelderland, Netherlands
Cefazolin-Lidocaine Combination Solution to Reduce Antibiotic Pain
- First Posted Date
- 2014-12-24
- Last Posted Date
- 2014-12-24
- Lead Sponsor
- University Health Network, Toronto
- Target Recruit Count
- 54
- Registration Number
- NCT02324166
The Combination of Adductor Canal Block and Periarticular Injection. A Novel Technique for Patients Undergoing Total Knee Replacement (ACB PAI)
- First Posted Date
- 2014-11-17
- Last Posted Date
- 2019-01-11
- Lead Sponsor
- Hospital for Special Surgery, New York
- Target Recruit Count
- 111
- Registration Number
- NCT02292082
- Locations
- 🇺🇸
Hospital for Special Surgery, New York, New York, United States
Prevention of Infections in Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2014-11-06
- Last Posted Date
- 2023-09-22
- Lead Sponsor
- Hamilton Health Sciences Corporation
- Target Recruit Count
- 3000
- Registration Number
- NCT02285140
- Locations
- 🇨🇦
Hamilton Health Sciences, Hamilton, Ontario, Canada
🇨🇦St. Michael's Hospital, Toronto, Ontario, Canada
🇨🇦Jewish Hospital, Montréal, Quebec, Canada
Checklist to Prevent MRSA Surgical Site Infections
- Conditions
- Interventions
- First Posted Date
- 2014-08-13
- Last Posted Date
- 2021-03-11
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 1794
- Registration Number
- NCT02216227
- Locations
- 🇺🇸
Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore, Maryland, United States
🇺🇸VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts, United States
🇺🇸VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan, United States
A Phase 3 Telavancin Staphylococcus Aureus (S. Aureus) Bacteremia Trial
- Conditions
- Interventions
- First Posted Date
- 2014-08-04
- Last Posted Date
- 2020-02-17
- Lead Sponsor
- Cumberland Pharmaceuticals
- Target Recruit Count
- 121
- Registration Number
- NCT02208063
- Locations
- 🇺🇸
Remington-Davis Clinical Research, Columbus, Ohio, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.