Polyethylene glycol

Generic Name
Polyethylene glycol
Brand Names
Bi-peglyte, Clearlax, Colyte, Gavilax, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Gentlelax, Gialax, Glycolax, Golytely, Healthylax, Miralax, Moviprep, Nulytely, Peglyte, Pegylax, Plenvu, Purelax, Suflave
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
25322-68-3
Unique Ingredient Identifier
3WJQ0SDW1A
Background

Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary by time of the polymerization process and the...

Indication

Polyethylene glycol is indicated for use as an over-the-counter osmotic laxative to relieve occasional constipation. When used in combination with sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride and potassium chloride, it is used for cleansing of the colon in preparation for colonoscopy in adults.

Associated Conditions
Chronic Constipation, Constipation, Dry Eye Syndrome (DES), Dry Eyes, Occasional Constipation
Associated Therapies
Bowel preparation therapy, Eye lubrication

Reduction of Postoperative Gastrointestinal Dysmotility Following Total Laparoscopic Hysterectomy.

First Posted Date
2019-01-11
Last Posted Date
2020-06-02
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
81
Registration Number
NCT03800745
Locations
🇺🇸

Cleveland Clinic Florida, Weston, Florida, United States

Study Comparing the Bowel Cleansing Efficacy of PLENVU® Versus SELG-ESSE® Using a 2-Day Split Dosing Regimen.

First Posted Date
2018-11-15
Last Posted Date
2020-08-27
Lead Sponsor
Istituto Clinico Humanitas
Target Recruit Count
399
Registration Number
NCT03742232
Locations
🇮🇹

ISMETT, Palermo, Italy

🇮🇹

Fondazione Poliambulanza, Brescia, Italia, Italy

🇮🇹

Humanitas Research Hospital, Rozzano, Italy

and more 2 locations

A Predictive Model for Inadequate Bowel Preparation

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2018-10-15
Last Posted Date
2019-11-01
Lead Sponsor
Shandong University
Target Recruit Count
429
Registration Number
NCT03704571
Locations
🇨🇳

Qilu Hospital of Shandong University, Jinan, Shandong, China

Dried Plums (Prunes) vs. Polyethylene Glycol 4000 for Treatment of Functional Constipation in Children

First Posted Date
2018-08-20
Last Posted Date
2018-08-23
Lead Sponsor
Medical University of Warsaw
Target Recruit Count
110
Registration Number
NCT03639142

Safety and Tolerability of PRO-087 Versus Xyel Ofteno® and Systane Ultra®, on the Ocular Surface of Healthy Subjects

First Posted Date
2018-05-14
Last Posted Date
2019-07-19
Lead Sponsor
Laboratorios Sophia S.A de C.V.
Target Recruit Count
30
Registration Number
NCT03524157
Locations
🇲🇽

Private Ophthalmological Office, Zapopan, Jalisco, Mexico

Evaluation of the Performance of Two Neutral Oral Contrast Agents in CT Enterography

Not Applicable
Conditions
Interventions
First Posted Date
2018-04-12
Last Posted Date
2018-08-24
Lead Sponsor
Shandong University
Target Recruit Count
60
Registration Number
NCT03495804
Locations
🇨🇳

Department of Gastroenterology, Qilu Hospital, Shandong University, Jinan, Shandong, China

Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease

First Posted Date
2018-03-26
Last Posted Date
2022-02-09
Lead Sponsor
Children's Hospital of Philadelphia
Target Recruit Count
10
Registration Number
NCT03476317
Locations
🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Stability of the Microbiome in IBD and IBS

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2018-01-10
Last Posted Date
2020-08-11
Lead Sponsor
Medical University of Graz
Target Recruit Count
50
Registration Number
NCT03395548
Locations
🇦🇹

Universitätsklinikum Graz, Graz, Styria, Austria

Effect of PEG, Bisacodyl and Prucalopride on Colonic Motility in Healthy Subjects

First Posted Date
2017-09-12
Last Posted Date
2017-09-12
Lead Sponsor
University Hospital, Gasthuisberg
Target Recruit Count
10
Registration Number
NCT03279341
Locations
🇧🇪

TARGID, Leuven, Belgium

Efficacy and Safety of the Ophthalmic Solution PRO-087 Versus Systane ® Ultra and Ultra Preservative Free (087LATAMFIV)

First Posted Date
2017-07-21
Last Posted Date
2019-10-31
Lead Sponsor
Laboratorios Sophia S.A de C.V.
Target Recruit Count
326
Registration Number
NCT03223909
Locations
🇲🇽

Fernando Rodriguez Sixtos Higuera, Irapuato, Guanajuato, Mexico

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