Doxapram
- Generic Name
- Doxapram
- Brand Names
- Dopram
- Drug Type
- Small Molecule
- Chemical Formula
- C24H30N2O2
- CAS Number
- 309-29-5
- Unique Ingredient Identifier
- 94F3830Q73
- Background
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
- Indication
For use as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.
- Associated Conditions
- Anesthetic complication pulmonary, Acute Hypercapnia, Drug-induced Respiratory depression, Postoperative respiratory depression
- Associated Therapies
- Post-operative respiratory stimulation therapy
Study to Investigate the Safety, Tolerability and Pharmacokinetics of QEV-817 Oral Suspension
- Conditions
- Healthy
- Interventions
- First Posted Date
- 2024-09-05
- Last Posted Date
- 2024-09-05
- Lead Sponsor
- Quivive Pharma, Inc.
- Target Recruit Count
- 8
- Registration Number
- NCT06585163
- Locations
- 🇺🇸
Cleveland Clinic Main Campus, Cleveland, Ohio, United States
Doxapram Therapy in Preterm Infants (DOXA Trial)
- Conditions
- Apnea of PrematurityRespiratory Insufficiency
- Interventions
- Drug: Placebo
- First Posted Date
- 2020-06-12
- Last Posted Date
- 2024-04-04
- Lead Sponsor
- Erasmus Medical Center
- Target Recruit Count
- 396
- Registration Number
- NCT04430790
- Locations
- 🇳🇱
Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands
🇧🇪Delta Hospital Brussels, Brussels, Brussels Hoofdstedelijk Gewest, Belgium
🇧🇪Academisch Ziekenhuis Sint-Jan, Brugge, West-Vlaanderen, Belgium
The Effect of Doxapram Versus Theophylline on Diaphragmatic Function
- First Posted Date
- 2019-03-28
- Last Posted Date
- 2019-03-28
- Lead Sponsor
- Beni-Suef University
- Target Recruit Count
- 70
- Registration Number
- NCT03894189
- Locations
- 🇪🇬
Beni-Suef University Hospital, Banī Suwayf, Egypt
The Effect and Mechanism of Respiratory Stimulant Doxapram on Facilitating Emergence
- First Posted Date
- 2016-06-30
- Last Posted Date
- 2017-01-18
- Lead Sponsor
- General Hospital of Ningxia Medical University
- Target Recruit Count
- 40
- Registration Number
- NCT02820025
- Locations
- 🇨🇳
Anesthesiology department of General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China
Doxapram as an Additive to Propofol Sedation in Sedation for ERCP
- First Posted Date
- 2014-06-24
- Last Posted Date
- 2016-12-05
- Lead Sponsor
- Helsinki University Central Hospital
- Target Recruit Count
- 50
- Registration Number
- NCT02171910
- Locations
- 🇫🇮
Helsinki University Central Hospital, Helsinki, Uusimaa, Finland
Aminophylline and Cognitive Function After Sevoflurane Anaesthesia
- Conditions
- Anaesthesia
- Interventions
- First Posted Date
- 2009-12-01
- Last Posted Date
- 2010-11-19
- Lead Sponsor
- King Faisal University
- Target Recruit Count
- 180
- Registration Number
- NCT01022151
- Locations
- 🇸🇦
King Faisal University, Khobar, Eastern, Saudi Arabia
Staccato Alprazolam in Panic Attack
- Conditions
- Treatment of Induced Panic Attack
- Interventions
- First Posted Date
- 2007-05-23
- Last Posted Date
- 2017-06-16
- Lead Sponsor
- Alexza Pharmaceuticals, Inc.
- Target Recruit Count
- 49
- Registration Number
- NCT00477451
- Locations
- 🇺🇸
SUNY Downstate Medical Center, Brooklyn, New York, United States
🇺🇸New York State Psychiatric Institute, New York, New York, United States
🇺🇸Mt. Sinai School Of Medicine, New York, New York, United States
Dosing Chart for Calculating the First Dose of Doxapram in Premature Infants
- First Posted Date
- 2006-10-19
- Last Posted Date
- 2017-02-27
- Lead Sponsor
- Jean Michel Hascoet
- Target Recruit Count
- 85
- Registration Number
- NCT00389909
- Locations
- 🇫🇷
Hopital des Enfants, Toulouse, France
🇫🇷Maternite Regionale Universitaire, Nancy, France
Drug Development Updates
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