Doxapram

Generic Name
Doxapram
Brand Names
Dopram
Drug Type
Small Molecule
Chemical Formula
C24H30N2O2
CAS Number
309-29-5
Unique Ingredient Identifier
94F3830Q73
Background

A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)

Indication

For use as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.

Associated Conditions
Anesthetic complication pulmonary, Acute Hypercapnia, Drug-induced Respiratory depression, Postoperative respiratory depression
Associated Therapies
Post-operative respiratory stimulation therapy
Clinical Trials
Related News

Doxapram Therapy in Preterm Infants (DOXA Trial)

First Posted Date
2020-06-12
Last Posted Date
2024-04-04
Lead Sponsor
Erasmus Medical Center
Target Recruit Count
396
Registration Number
NCT04430790
Locations
🇳🇱

Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands

🇧🇪

Delta Hospital Brussels, Brussels, Brussels Hoofdstedelijk Gewest, Belgium

🇧🇪

Academisch Ziekenhuis Sint-Jan, Brugge, West-Vlaanderen, Belgium

and more 21 locations

The Effect and Mechanism of Respiratory Stimulant Doxapram on Facilitating Emergence

Not Applicable
Conditions
Anesthesia
Interventions
Drug: doxapram
Other: saline
First Posted Date
2016-06-30
Last Posted Date
2017-01-18
Lead Sponsor
General Hospital of Ningxia Medical University
Target Recruit Count
40
Registration Number
NCT02820025
Locations
🇨🇳

Anesthesiology department of General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China

Doxapram as an Additive to Propofol Sedation in Sedation for ERCP

Phase 4
Completed
Conditions
Sedation
Hypoxia
Interventions
Drug: Placebo
Drug: Doxapram
First Posted Date
2014-06-24
Last Posted Date
2016-12-05
Lead Sponsor
Helsinki University Central Hospital
Target Recruit Count
50
Registration Number
NCT02171910
Locations
🇫🇮

Helsinki University Central Hospital, Helsinki, Uusimaa, Finland

Dosing Chart for Calculating the First Dose of Doxapram in Premature Infants

Phase 4
Completed
Conditions
Premature Infants
Apnea
Interventions
Drug: Doxapram
First Posted Date
2006-10-19
Last Posted Date
2017-02-27
Lead Sponsor
Jean Michel Hascoet
Target Recruit Count
85
Registration Number
NCT00389909
Locations
🇫🇷

Hopital des Enfants, Toulouse, France

🇫🇷

Maternite Regionale Universitaire, Nancy, France

© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy