Moxifloxacin

Generic Name
Moxifloxacin
Brand Names
Avelox, Moxeza, Vigamox
Drug Type
Small Molecule
Chemical Formula
C21H24FN3O4
CAS Number
151096-09-2
Unique Ingredient Identifier
U188XYD42P
Background

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

Indication

For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).

Associated Conditions
Acute Exacerbation of Chronic Bronchitis (AECB), Bacterial Conjunctivitis, Community Acquired Pneumonia (CAP), Plague, Postoperative Infections, Postoperative Inflammatory Response, Sinusitis, Skin Infections, Ocular bacterial infections
Associated Therapies
-

A Study of the Effect of RO4917838 on the QTcF Interval in Healthy Volunteers

First Posted Date
2012-06-06
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
169
Registration Number
NCT01613040

A Study Measuring Effect of LY2140023 (Pomaglumetad Methionil) on Electrocardiographs in Participants With Schizophrenia

First Posted Date
2012-05-25
Last Posted Date
2023-04-03
Lead Sponsor
Denovo Biopharma LLC
Target Recruit Count
86
Registration Number
NCT01606436
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Austin, Texas, United States

CAEB071 Thorough QTc Study in Healthy Volunteers

First Posted Date
2012-05-09
Last Posted Date
2012-05-09
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
100
Registration Number
NCT01594255
Locations
🇺🇸

Novartis Investigational Site, Austin, Texas, United States

Essentiality of INH in TB Therapy

First Posted Date
2012-05-02
Last Posted Date
2018-04-06
Lead Sponsor
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Target Recruit Count
69
Registration Number
NCT01589497
Locations
🇿🇦

TASK Applied Science CRS (31718), Bellville, South Africa

🇿🇦

University of Cape Town Lung Institute (UCTLI) CRS (31792), Cape Town, Western Cape, South Africa

Study of the Effect of Repeat Doses of Isavuconazole on Cardiac Repolarization

First Posted Date
2012-03-29
Last Posted Date
2012-07-09
Lead Sponsor
Astellas Pharma Global Development, Inc.
Target Recruit Count
161
Registration Number
NCT01565720
Locations
🇺🇸

Parexel, Glendale, California, United States

Effect of Anagrelide Hydrochloride on Any Changes in Heart Function in Healthy Volunteers

First Posted Date
2012-03-13
Last Posted Date
2021-06-09
Lead Sponsor
Shire
Target Recruit Count
60
Registration Number
NCT01552928
Locations
🇫🇷

Biotrial, Rueil-Malmaison, France

A Study of LY2484595 on the Electrical Activity of the Heart

First Posted Date
2012-02-23
Last Posted Date
2019-03-07
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
72
Registration Number
NCT01537887
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Evansville, Indiana, United States

A Study of LY3009104 in Healthy Participants

First Posted Date
2012-02-22
Last Posted Date
2017-06-06
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
62
Registration Number
NCT01536951
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Daytona Beach, Florida, United States

Effect of BIA 9-1067 on Cardiac Repolarization in Healthy Adult Men and Women

First Posted Date
2012-02-14
Last Posted Date
2012-06-21
Lead Sponsor
Bial - Portela C S.A.
Target Recruit Count
64
Registration Number
NCT01532115
Locations
🇫🇷

Biotrial, 7-9 rue Jean-Louis Bertrand, Rennes, France

QTc Study GSK573719+GW642444

First Posted Date
2012-01-30
Last Posted Date
2017-06-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
100
Registration Number
NCT01521377
Locations
🇬🇧

GSK Investigational Site, London, United Kingdom

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