Primaquine
- Generic Name
- Primaquine
- Drug Type
- Small Molecule
- Chemical Formula
- C15H21N3O
- CAS Number
- 90-34-6
- Unique Ingredient Identifier
- MVR3634GX1
- Background
An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
- Indication
For the treatment of malaria.
- Associated Conditions
- Malaria, Malaria caused by Plasmodium ovale, Malaria caused by plasmodium vivax, Pneumocystis Jirovecii Pneumonia
Eight Week Primaquine Regimen for the Treatment of Vivax Malaria
- Conditions
- Vivax MalariaMalaria
- First Posted Date
- 2005-09-12
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 150
- Registration Number
- NCT00158587
A Test to Predict the Hemolytic Potential of Drugs in G6PD Deficiency
- Conditions
- Glucosephosphate Dehydrogenase DeficiencyFavism
- First Posted Date
- 2004-01-21
- Last Posted Date
- 2010-07-27
- Lead Sponsor
- Walter Reed Army Institute of Research (WRAIR)
- Target Recruit Count
- 14
- Registration Number
- NCT00076323
- Locations
- 🇺🇸
Walter Reed Army Institute of Research, Silver Spring, Maryland, United States
The Safety and Efficacy of Clindamycin and Primaquine in the Treatment of Mild - Moderate Pneumocystis Carinii Pneumonia in Patients With AIDS
- Conditions
- HIV InfectionsPneumonia, Pneumocystis Carinii
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2012-10-19
- Target Recruit Count
- 50
- Registration Number
- NCT00000717
- Locations
- 🇺🇸
Northwestern Univ Med School, Chicago, Illinois, United States
🇺🇸Los Angeles County - USC Med Ctr, Los Angeles, California, United States
🇺🇸San Francisco AIDS Clinic / San Francisco Gen Hosp, San Francisco, California, United States
A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS
- Conditions
- HIV InfectionsPneumonia, Pneumocystis Carinii
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-03
- Target Recruit Count
- 290
- Registration Number
- NCT00000640
- Locations
- 🇺🇸
Johns Hopkins Adult AIDS CRS, Baltimore, Maryland, United States
🇺🇸Methodist Hosp. of Indiana, Indianapolis, Indiana, United States
🇺🇸Massachusetts General Hospital ACTG CRS, Boston, Massachusetts, United States
Drug Development Updates
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