Primaquine
- Generic Name
- Primaquine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C15H21N3O
- CAS Number
- 90-34-6
- Unique Ingredient Identifier
- MVR3634GX1
- Background
An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI dis...
- Indication
For the treatment of malaria.
- Associated Conditions
- Malaria, Malaria caused by Plasmodium ovale, Malaria caused by plasmodium vivax, Pneumocystis Jirovecii Pneumonia
- Associated Therapies
- -
Safety and Efficacy of Chloroquine and Primaquine for Vivax Malaria in Bhutan
- First Posted Date
- 2012-10-29
- Last Posted Date
- 2016-05-27
- Lead Sponsor
- Menzies School of Health Research
- Target Recruit Count
- 24
- Registration Number
- NCT01716260
- Locations
- 🇧🇹
Vector Diseases Control Program, Gelephu, Bhutan
P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine
- Conditions
- Interventions
- First Posted Date
- 2012-10-17
- Last Posted Date
- 2015-04-09
- Lead Sponsor
- Menzies School of Health Research
- Target Recruit Count
- 250
- Registration Number
- NCT01708876
- Locations
- 🇲🇾
Kudat District Hospital, Kudat, Sabah, Malaysia
🇲🇾Kota Marudu District Hospital, Kota Marudu, Sabah, Malaysia
🇲🇾Pitas District Hospital, Pitas, Sabah, Malaysia
Ethiopia Antimalarial in Vivo Efficacy Study 2012
- Conditions
- Interventions
- First Posted Date
- 2012-09-07
- Last Posted Date
- 2017-01-19
- Lead Sponsor
- Centers for Disease Control and Prevention
- Target Recruit Count
- 398
- Registration Number
- NCT01680406
- Locations
- 🇪🇹
Bishoftu Malaria Center, Debre Zeit, Ethiopia
🇪🇹Batu Health Center, Zeway, Ethiopia
Malaria Challenge in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2011-12-29
- Last Posted Date
- 2012-12-13
- Lead Sponsor
- Seattle Children's Hospital
- Target Recruit Count
- 36
- Registration Number
- NCT01500980
- Locations
- 🇺🇸
Seattle Biomedical Research Institute's Malaria Clinical Trials Center, Seattle, Washington, United States
Evaluation of the Gametocytocidal Efficacy and Safety of Primaquine in Uncomplicated Falciparum Malaria in Uganda
- First Posted Date
- 2011-06-03
- Last Posted Date
- 2013-06-12
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 468
- Registration Number
- NCT01365598
- Locations
- 🇺🇬
Walukuba Health Centre IV, Jinja, Eastern Region, Uganda
G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine)
- First Posted Date
- 2010-09-20
- Last Posted Date
- 2017-06-07
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 192
- Registration Number
- NCT01205178
- Locations
- 🇹🇭
GSK Investigational Site, Tak, Thailand
Incidence of Vivax Along the Thai Burma Border
- First Posted Date
- 2010-02-26
- Last Posted Date
- 2023-01-17
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 403
- Registration Number
- NCT01076868
- Locations
- 🇹🇭
Shoklo Malaria Research Unit, Mae Sot, Tak, Thailand
Eight Week Primaquine Regimen for the Treatment of Vivax Malaria
- Conditions
- First Posted Date
- 2005-09-12
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 150
- Registration Number
- NCT00158587
A Test to Predict the Hemolytic Potential of Drugs in G6PD Deficiency
- Conditions
- First Posted Date
- 2004-01-21
- Last Posted Date
- 2010-07-27
- Lead Sponsor
- Walter Reed Army Institute of Research (WRAIR)
- Target Recruit Count
- 14
- Registration Number
- NCT00076323
- Locations
- 🇺🇸
Walter Reed Army Institute of Research, Silver Spring, Maryland, United States
The Safety and Efficacy of Clindamycin and Primaquine in the Treatment of Mild - Moderate Pneumocystis Carinii Pneumonia in Patients With AIDS
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2012-10-19
- Target Recruit Count
- 50
- Registration Number
- NCT00000717
- Locations
- 🇺🇸
Northwestern Univ Med School, Chicago, Illinois, United States
🇺🇸Los Angeles County - USC Med Ctr, Los Angeles, California, United States
🇺🇸San Francisco AIDS Clinic / San Francisco Gen Hosp, San Francisco, California, United States
Drug Development Updates
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