Primaquine
- Generic Name
- Primaquine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C15H21N3O
- CAS Number
- 90-34-6
- Unique Ingredient Identifier
- MVR3634GX1
- Background
An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI dis...
- Indication
For the treatment of malaria.
- Associated Conditions
- Malaria, Malaria caused by Plasmodium ovale, Malaria caused by plasmodium vivax, Pneumocystis Jirovecii Pneumonia
- Associated Therapies
- -
An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and Older
- Conditions
- Interventions
- First Posted Date
- 2024-10-30
- Last Posted Date
- 2024-12-13
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 300
- Registration Number
- NCT06666491
- Locations
- 🇮🇳
GSK Investigational Site, Surat, India
A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)
- Conditions
- Interventions
- First Posted Date
- 2024-03-06
- Last Posted Date
- 2024-06-27
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 42
- Registration Number
- NCT06294912
- Locations
- 🇦🇺
USC Clinical Trials Brisbane (South Bank) ( Site 0001), South Brisbane, South Australia, Australia
Postpartum Primaquine in Breast Milk
- First Posted Date
- 2024-01-05
- Last Posted Date
- 2024-03-19
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 12
- Registration Number
- NCT06191458
- Locations
- 🇹🇭
Shoklo Malaria Research Unit (SMRU), Mae Ramat, Tak, Thailand
A Revised Tafenoquine Dose to Improve Radical Cure for Vivax Malaria
- First Posted Date
- 2023-11-28
- Last Posted Date
- 2024-08-29
- Lead Sponsor
- Menzies School of Health Research
- Target Recruit Count
- 1090
- Registration Number
- NCT06148792
- Locations
- 🇪🇹
Arba Minch General Hospital, Arba Minch, Ethiopia
🇵🇬Dr Moses Laman and Dr Brioni Moore, Alexishafen, Papua New Guinea
🇮🇩Dr Rini Poespoprodjo, Timika, Indonesia
Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium Vivax
- Conditions
- Interventions
- First Posted Date
- 2023-09-21
- Last Posted Date
- 2023-09-22
- Lead Sponsor
- Dinka Dugassa
- Target Recruit Count
- 100
- Registration Number
- NCT06044805
- Locations
- 🇪🇹
Shecha Health Center, Arba Minch, South Ethiopia, Ethiopia
Combination Momordica Charantia Extract and Primaquine Againts Plasmodium Falciparum Uncomplicated and Plasmodium Vivax Uncomplicated Treatment in Manokwari, West Papua
- First Posted Date
- 2023-09-13
- Last Posted Date
- 2023-09-13
- Lead Sponsor
- Syamsudin Abdillah,Ph.D, Pharm D
- Target Recruit Count
- 50
- Registration Number
- NCT06036030
- Locations
- 🇮🇩
Manokwari Regional General Hospital, Manokwari, West Papua, Indonesia
TES of Chloroquine for Pv in the Philippines in 2016
- First Posted Date
- 2023-07-25
- Last Posted Date
- 2023-07-25
- Target Recruit Count
- 74
- Registration Number
- NCT05958797
TES of Artemether-lumefantrine for Pf in the Philippines in 2017-2018
- Conditions
- Interventions
- First Posted Date
- 2023-07-25
- Last Posted Date
- 2023-07-25
- Target Recruit Count
- 80
- Registration Number
- NCT05958810
TES of Artemether-lumefantrine for Pf in the Philippines in 2015
- Conditions
- Interventions
- First Posted Date
- 2023-07-24
- Last Posted Date
- 2023-07-24
- Target Recruit Count
- 82
- Registration Number
- NCT05958693
Momordica Charantia and Dihydroartemisinin-piperaquined-primaquine for Uncomplicated Plasmodium Falciparum Malaria Patients in Southwest Sumba Regency
- Conditions
- Interventions
- First Posted Date
- 2023-04-25
- Last Posted Date
- 2023-05-16
- Lead Sponsor
- Syamsudin Abdillah,Ph.D, Pharm D
- Target Recruit Count
- 36
- Registration Number
- NCT05829187
- Locations
- 🇮🇩
Kori Puskesmas, Tambolaka, East Nusa Tenggara, Indonesia
Drug Development Updates
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