Skin Immunity Sample Collection Involving Blisters and Biopsies
- Conditions
- Hyper-Immunoglobulin E. Syndrome (HEIS)Chronic Granulomatous Disease (CGD)
- Interventions
- Other: Blister inductionOther: Skin Biopsies
- First Posted Date
- 2019-04-19
- Last Posted Date
- 2024-12-13
- Target Recruit Count
- 70
- Registration Number
- NCT03921515
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Pfs230D1M-EPA/AS01 Vaccine, a Transmission Blocking Vaccine Against Plasmodium Falciparum, in an Age De-Escalation Trial of Children and a Family Compound Trial in Mali
- Conditions
- Malaria
- Interventions
- Biological: TYPHIM Vi (Salmonella typhi vaccine)
- First Posted Date
- 2019-04-17
- Last Posted Date
- 2024-10-22
- Target Recruit Count
- 1301
- Registration Number
- NCT03917654
- Locations
- 🇲🇱
Mrtc/Usttb, Bamako, Mali
Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L, RSV 6120/ΔNS2/1030s, RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Children 6 to 24 Months of Age
- Conditions
- Respiratory Syncytial Virus (RSV)
- Interventions
- Biological: RSV 6120/ΔNS2/1030s VaccineBiological: RSV 276 VaccineBiological: PlaceboBiological: RSV ΔNS2/Δ1313/I1314L Vaccine
- First Posted Date
- 2019-04-16
- Last Posted Date
- 2025-02-21
- Target Recruit Count
- 67
- Registration Number
- NCT03916185
- Locations
- 🇺🇸
University of Maryland School of Medicine Center for Vaccine Development CRS, Baltimore, Maryland, United States
🇺🇸Gamble Center for Clinical Studies CRS, Cincinnati, Ohio, United States
🇺🇸Baylor College of Medicine/ Texas Children's Hospital NICHD CRS, Houston, Texas, United States
Intravenous Fosfomycin Pharmacokinetics Study
- Conditions
- Multiple-drug ResistancePathogen ResistanceBacterial Infection
- Interventions
- First Posted Date
- 2019-04-10
- Last Posted Date
- 2023-10-23
- Target Recruit Count
- 39
- Registration Number
- NCT03910673
- Locations
- 🇺🇸
Duke Human Vaccine Institute - Duke Vaccine and Trials Unit, Durham, North Carolina, United States
Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide
- Conditions
- Chronic Granulomatous Disease
- Interventions
- Radiation: Total Body IrradiationBiological: Allogeneic peripheral blood stem cell
- First Posted Date
- 2019-04-10
- Last Posted Date
- 2025-03-06
- Target Recruit Count
- 4
- Registration Number
- NCT03910452
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
🇺🇸National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Dried Blood Spot Testing of CMV Detection in HCT Recipients
- Conditions
- Cytomegalovirus Infection
- Interventions
- Device: DBS Self-Collection KitOther: Standard Control Strategy
- First Posted Date
- 2019-04-10
- Last Posted Date
- 2025-03-13
- Target Recruit Count
- 622
- Registration Number
- NCT03910478
- Locations
- 🇺🇸
The University of Texas - MD Anderson Cancer Center - Infectious Diseases, Houston, Texas, United States
🇺🇸Fred Hutchinson Cancer Research Center - Vaccine and Infectious Diseases, Seattle, Washington, United States
🇺🇸University of Minnesota Medical Center, Fairview - Infectious Diseases and International Medicine, Minneapolis, Minnesota, United States
An Observational Study to Assess the Prevalence and Outcomes of Primary Pulmonary Coccidioidomycosis in Persons Aged > / = 14 Years Presenting With Community Acquired Pneumonia (CAP) in Endemic Areas (SAnds-PPC)
- Conditions
- CoccidioidomycosisPneumonia
- First Posted Date
- 2019-04-09
- Last Posted Date
- 2024-01-19
- Target Recruit Count
- 651
- Registration Number
- NCT03908632
- Locations
- 🇺🇸
Kaiser Permanente Antelope Valley Medical Offices - Infectious Diseases, Lancaster, California, United States
🇺🇸Kaiser Permanente Chester Avenue Medical Offices - Pulmonology, Bakersfield, California, United States
🇺🇸Banner - University Medical Center Advanced Lung Disease Clinic - Phoenix, Phoenix, Arizona, United States
Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal Function
- First Posted Date
- 2019-04-01
- Last Posted Date
- 2025-05-06
- Target Recruit Count
- 12
- Registration Number
- NCT03896750
- Locations
- 🇺🇸
Advanced Pharma - Miami, Miami, Florida, United States
🇺🇸Saint Louis University Center for Vaccine Development, Saint Louis, Missouri, United States
🇺🇸Alliance for Multispecialty Research, LLC - Knoxville, Knoxville, Tennessee, United States
Connors Protocol for the Management and Use of Stored Human Specimens (Stored Human Specimens)
- Conditions
- Healthy Volunteer Samples
- First Posted Date
- 2019-03-29
- Last Posted Date
- 2025-05-23
- Target Recruit Count
- 1000
- Registration Number
- NCT03895645
- Locations
- 🇺🇸
National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, United States
A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and Rifabutin
- First Posted Date
- 2019-03-27
- Last Posted Date
- 2023-10-23
- Target Recruit Count
- 24
- Registration Number
- NCT03891901
- Locations
- 🇺🇸
Emory University DAIDS TB Non-Network CRS, Atlanta, Georgia, United States