MedPath

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

🇺🇸United States
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Employees
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Market Cap
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Website

Safety/Efficacy Study of Seqirus A/H7N9 IIV With or Without MF59(R) Adjuvant to Prevent Avian Influenza

Phase 2
Completed
Conditions
Avian Influenza
Influenza Immunisation
Interventions
Biological: A/H7N9
Drug: MF59
Other: Phosphate Buffered Saline (PBS) diluent
First Posted Date
2018-09-24
Last Posted Date
2021-05-17
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
372
Registration Number
NCT03682120
Locations
🇺🇸

Baylor College of Medicine - Molecular Virology and Microbiology, Houston, Texas, United States

🇺🇸

Kaiser Permanente Washington Health Research Institute - Vaccines and Infectious Diseases, Seattle, Washington, United States

🇺🇸

University of Alabama at Birmingham School of Medicine - Alabama Vaccine Research Clinic, Birmingham, Alabama, United States

and more 4 locations

Andes Virus DNA Vaccine for the Prevention of Hantavirus Pulmonary Syndrome Using the PharmaJet Stratis(R) Needle-Free Injection Delivery Device

Phase 1
Completed
Conditions
Immunisation
Hantavirus Pulmonary Infection
Interventions
Biological: Andes virus DNA vaccine
Other: Placebo
First Posted Date
2018-09-24
Last Posted Date
2022-11-22
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
48
Registration Number
NCT03682107
Locations
🇺🇸

Cincinnati Children's Hospital Medical Center - Infectious Diseases, Cincinnati, Ohio, United States

Development of Childhood Anti-Influenza Immunity

Phase 4
Completed
Conditions
Influenza
Influenza Immunisation
Interventions
Biological: Influenza Virus Quadrivalent Inactivated Vaccine
First Posted Date
2018-09-17
Last Posted Date
2022-03-18
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
125
Registration Number
NCT03673345
Locations
🇺🇸

University of Rochester Medical Center - Strong Memorial Hospital - Infectious Diseases, Rochester, New York, United States

Pharmacokinetic and Safety Study of a 90 Day Intravaginal Ring Containing Tenofovir

Phase 1
Completed
Conditions
HIV Infections
Interventions
Drug: Tenofovir (TFV) IVR
Drug: Placebo IVR
First Posted Date
2018-09-13
Last Posted Date
2022-05-03
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
49
Registration Number
NCT03670355
Locations
🇺🇸

Bridge HIV CRS, San Francisco, California, United States

🇺🇸

Alabama CRS, Birmingham, Alabama, United States

🇺🇸

University of Pittsburgh CRS, Pittsburgh, Pennsylvania, United States

Liver Transplantation With Tregs at UCSF

Phase 1
Terminated
Conditions
Liver Transplant
Interventions
Biological: arTreg
Procedure: leukapheresis
Drug: cyclophosphamide
Drug: mesna
Drug: everolimus
First Posted Date
2018-08-31
Last Posted Date
2024-04-23
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
42
Registration Number
NCT03654040
Locations
🇺🇸

University of California, San Francisco, San Francisco, California, United States

Tocilizumab in Cardiac Transplantation

Phase 2
Active, not recruiting
Conditions
Heart Transplant
Interventions
Biological: Placebo
Biological: tocilizumab
Drug: Standard of Care Triple IS
First Posted Date
2018-08-23
Last Posted Date
2024-03-26
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
385
Registration Number
NCT03644667
Locations
🇺🇸

Hospital of the University of Pennsylvania (PAUP), Philadelphia, Pennsylvania, United States

🇺🇸

Allegheny General Hospital (PAAG), Pittsburgh, Pennsylvania, United States

🇺🇸

Baylor University Medical Center (TXTX), Dallas, Texas, United States

and more 17 locations

Defining Skin Immunity of a Bite of Key Insect Vectors in Humans

Not Applicable
Completed
Conditions
Malaria
Zika
Chikungunya
Leishmaniasis
Dengue
Interventions
Other: Four vector feeding
Other: One vector feeding
First Posted Date
2018-08-22
Last Posted Date
2021-12-08
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
95
Registration Number
NCT03641339
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV Infection

Phase 4
Completed
Conditions
Syphilis
Interventions
Drug: Benzathine Penicillin
First Posted Date
2018-08-20
Last Posted Date
2023-12-26
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
249
Registration Number
NCT03637660
Locations
🇺🇸

Fenway Health - The Fenway Institute, Boston, Massachusetts, United States

🇺🇸

Magee Women's Hospital of UPMC - Reproductive Infectious Disease Research, Pittsburgh, Pennsylvania, United States

🇺🇸

University of Washington - Harborview Medical Center - Center for AIDS and STD, Seattle, Washington, United States

and more 7 locations

The LATITUDE Study: Long-Acting Therapy to Improve Treatment SUccess in Daily LifE

Phase 3
Active, not recruiting
Conditions
HIV Infections
Interventions
Drug: Standard of Care (SOC) Oral ART
Drug: Oral RPV
Drug: Oral CAB
Drug: RPV-LA Loading Dose
Drug: CAB-LA Loading Dose
Drug: RPV-LA Maintenance Dose
Drug: CAB-LA Maintenance Dose
First Posted Date
2018-08-17
Last Posted Date
2024-11-20
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
310
Registration Number
NCT03635788
Locations
🇺🇸

University of Pittsburgh CRS, Pittsburgh, Pennsylvania, United States

🇺🇸

Northwestern University CRS, Chicago, Illinois, United States

🇺🇸

Brigham and Women's Hospital Therapeutics Clinical Research Site (BWH TCRS) CRS, Boston, Massachusetts, United States

and more 28 locations

Inpatient Challenge Study of rRSV A/Maryland/001/11, a Human Respiratory Syncytial Virus Challenge Strain, Administered to Healthy Adult Volunteers

Phase 1
Recruiting
Conditions
Respiratory Syncytial Virus Infections
Interventions
Biological: rRSV A/Maryland/001/11
First Posted Date
2018-08-10
Last Posted Date
2024-05-21
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
40
Registration Number
NCT03624790
Locations
🇺🇸

Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States

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