MedPath

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

🇺🇸United States
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Employees
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rCSP/AP10-602 [GLA-LSQ] Vaccine Trial

Phase 1
Completed
Conditions
Plasmodium Falciparum Infection
Interventions
Other: AP10-602
Other: Malaria challenge
Biological: rCSP
First Posted Date
2018-07-18
Last Posted Date
2023-07-10
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
65
Registration Number
NCT03589794
Locations
🇺🇸

University of Maryland, School of Medicine, Center for Vaccine Development and Global Health, Baltimore, Maryland, United States

Study on the Safety and Immunogenicity of Boostrix Vaccine in Pregnant Malian Women and Their Infants

Phase 2
Completed
Conditions
Diphtheria Immunisation
Clostridium Difficile Immunisation
Diphtheria
Tetanus
Tetanus Immunisation
Pertussis
Interventions
Biological: Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbed onto aluminum hydroxide
Biological: Tetanus and Diphtheria Toxoids Adsorbed
First Posted Date
2018-07-18
Last Posted Date
2023-01-20
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
399
Registration Number
NCT03589768
Locations
🇲🇱

Center for Vaccine Development - Mali, Bamako, Mali

A Trial to Evaluate the Safety and Systems Biology Response of Ebolavirus Zaire Vaccine (ChAd3-EBO-Z)

Phase 1
Completed
Conditions
Immunisation
Ebola Disease
Interventions
Biological: ChAd3-EBO-Z
Other: Placebo
Biological: MVA Multi-Filo Ebola Vaccine
First Posted Date
2018-07-11
Last Posted Date
2024-03-25
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
61
Registration Number
NCT03583606
Locations
🇺🇸

Cincinnati Children's Hospital Medical Center Vaccine Research Center, Cincinnati, Ohio, United States

A Study in Healthy Adults to Assess Priming With Antigenically Mismatched Live Attenuated A/H7N3 Influenza Virus Vaccine Followed by Inactivated A/H7N9 Influenza Virus Vaccine

Phase 1
Completed
Conditions
Influenza
Interventions
Biological: H7N3 pLAIV
Biological: H7N9 pIIV
First Posted Date
2018-07-10
Last Posted Date
2019-03-25
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
20
Registration Number
NCT03581903
Locations
🇺🇸

University of Rochester Medical Center Vaccine Research Unit (Outpatient), Rochester, New York, United States

Liver Transplantation With Tregs at MGH

Phase 1
Active, not recruiting
Conditions
Liver Transplant
Interventions
Biological: arTreg-CSB
Procedure: leukapheresis
Drug: cyclophosphamide
Drug: mesna
Drug: everolimus
First Posted Date
2018-07-05
Last Posted Date
2023-12-08
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
9
Registration Number
NCT03577431
Locations
🇺🇸

Massachusetts General Hospital: Transplantation, Boston, Massachusetts, United States

Combination Therapy With 3BNC117 and 10-1074 in HIV-Infected Individuals

Phase 1
Terminated
Conditions
HIV
Interventions
Biological: Placebo
Biological: 3BNC117 and 10-1074
First Posted Date
2018-06-27
Last Posted Date
2022-02-09
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
27
Registration Number
NCT03571204
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients

Phase 3
Recruiting
Conditions
Tuberculosis, MDR
Interventions
Drug: Delamanid (DLM)
Drug: Isoniazid (INH)
Dietary Supplement: Pyridoxine (vitamin B6)
First Posted Date
2018-06-26
Last Posted Date
2024-06-11
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
5610
Registration Number
NCT03568383
Locations
🇵🇭

De La Salle Health Science Institute Angelo King Medical Research Center (DLSHSI-AKMRC), Cavite, Philippines

🇹🇭

Chiangrai Prachanukroh Hospital NICHD CRS, Chiang Mai, Thailand

🇰🇪

Kenya Medical Research Institute/Walter Reed Project Clinical Research Center (KEMRI/WRP) CRS, Kericho, Rift Valley, Kenya

and more 29 locations

Vaginal Microbiome Exposure and Immune Responses in C-section Infants

Early Phase 1
Active, not recruiting
Conditions
Allergic Diseases
Asthma
Interventions
Biological: C-section -Vaginal seeding
Drug: C-section - Placebo Seeding
Other: standard care
First Posted Date
2018-06-26
Last Posted Date
2024-10-18
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
114
Registration Number
NCT03567707
Locations
🇺🇸

Mount Sinai West, New York, New York, United States

🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

Phase I Study to Evaluate a Human Monoclonal Antibody (MAb) 10E8VLS Administered Alone or Concurrently With MAb VRC07-523LS Via Subcutaneous Injection in Healthy Adults

Phase 1
Terminated
Conditions
Healthy Adult Immune Response
Interventions
Biological: VRC-HIVMAB095-00-AB (10E8VLS)
Biological: VRC-HIVMAB075-00-AB (VRC07-523LS)
First Posted Date
2018-06-21
Last Posted Date
2020-12-30
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
9
Registration Number
NCT03565315
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

HIV-1-Gag Conserved-Element DNA Vaccine (p24CE) Vaccine Study

Phase 1
Completed
Conditions
HIV Infections
Interventions
Biological: Full-length p55^gag pDNA vaccine
Biological: Placebo
Biological: p24CE1/2 pDNA vaccine
Biological: p24CE1/2 pDNA vaccine admixed with full-length p55^gag pDNA vaccine
First Posted Date
2018-06-18
Last Posted Date
2022-04-26
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
45
Registration Number
NCT03560258
Locations
🇺🇸

Northwestern University CRS, Chicago, Illinois, United States

🇺🇸

Ohio State University CRS, Columbus, Ohio, United States

🇺🇸

UCLA CARE Center CRS, Los Angeles, California, United States

and more 12 locations
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