Evaluating HIV-1 Neutralization Antibody Breadth in Response to HIV gp120 Protein Vaccine in HIV-uninfected Adults With Quiescent Systemic Lupus Erythematosus
- Conditions
- HIV InfectionsSystemic Lupus Erythematosus
- Interventions
- Biological: AIDSVAX® B/E
- First Posted Date
- 2018-08-07
- Last Posted Date
- 2022-02-07
- Target Recruit Count
- 1
- Registration Number
- NCT03618056
- Locations
- 🇺🇸
Duke Human Vaccine Institute CRS, Durham, North Carolina, United States
Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female Subjects
- Conditions
- Gonococcal InfectionElectrocardiogram Repolarisation Abnormality
- Interventions
- First Posted Date
- 2018-08-03
- Last Posted Date
- 2020-03-27
- Target Recruit Count
- 72
- Registration Number
- NCT03613649
- Locations
- 🇺🇸
Vince and Associates Clinical Research, Overland Park, Kansas, United States
Evaluation of the Safety and Immunogenicity of the Live Attenuated Zika Vaccine rZIKV/D4Δ30-713 in Flavivirus-naïve Adults
- Conditions
- Zika Virus
- Interventions
- Biological: PlaceboBiological: rZIKV/D4Δ30-713 (Administered at a dose of 10^3 plaque-forming units (PFUs) by subcutaneous injection)Biological: rZIKV/D4Δ30-713 (Administered at a dose of using 10^4 plaque-forming units (PFUs) by subcutaneous injection).
- First Posted Date
- 2018-08-02
- Last Posted Date
- 2022-06-03
- Target Recruit Count
- 56
- Registration Number
- NCT03611946
- Locations
- 🇺🇸
Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, United States
🇺🇸University of Vermont Medical Center (UVMMC), Clinical Research Center, Burlington, Vermont, United States
Trial of Azithromycin vs. Doxycycline for the Treatment of Rectal Chlamydia in MSM
- Conditions
- Anal Chlamydia Infection
- Interventions
- First Posted Date
- 2018-08-01
- Last Posted Date
- 2021-01-07
- Target Recruit Count
- 177
- Registration Number
- NCT03608774
- Locations
- 🇺🇸
University of Washington - Harborview Medical Center - Center for AIDS and STD, Seattle, Washington, United States
🇺🇸Fenway Health - The Fenway Institute, Boston, Massachusetts, United States
Send-In Sample Collection to Achieve Genetic and Immunologic Characterization of Primary Immunodeficiencies
- Conditions
- Primary Immunodeficiency
- First Posted Date
- 2018-08-01
- Last Posted Date
- 2024-12-06
- Target Recruit Count
- 3000
- Registration Number
- NCT03610802
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
🇮🇹Pavia Hospital (PH), Pavia, Italy
🇹🇷Marmara University Hospital, Istanbul Jeffrey Modell Diagnostic and Research Cen, Istanbul, Turkey
A Study to Evaluate the Safety and Pharmacokinetics of NTM-1633 vs Placebo Administered Intravenously in Healthy Adults
- Conditions
- Botulism
- Interventions
- Biological: NTM-1633Other: Placebo
- First Posted Date
- 2018-07-27
- Last Posted Date
- 2022-06-22
- Target Recruit Count
- 24
- Registration Number
- NCT03603665
- Locations
- 🇺🇸
Duke University School of Medicine - Duke Clinical Research Institute - Duke Clinical Research Unit, Durham, North Carolina, United States
Evaluating the Infectivity, Safety and Immunogenicity of Respiratory Syncytial Virus Vaccines, RSV 6120/∆NS1 and RSV 6120/F1/G2/∆NS1, in RSV-Seropositive Children and RSV-Seronegative Infants and Children
- Conditions
- RSV Infection
- Interventions
- Biological: RSV 6120/∆NS1Biological: RSV 6120/F1/G2/∆NS1Biological: Placebo
- First Posted Date
- 2018-07-24
- Last Posted Date
- 2024-08-29
- Target Recruit Count
- 60
- Registration Number
- NCT03596801
- Locations
- 🇺🇸
Johns Hopkins University Center for Immunization Research, Baltimore, Maryland, United States
Clinical Study of a Single-Use, Point-of-Care Molecular Diagnostic Device for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) Utilizing Vaginal Swabs
- Conditions
- GonorrhoeaChlamydial InfectionTrichomoniasis
- Interventions
- Device: Click Device
- First Posted Date
- 2018-07-23
- Last Posted Date
- 2021-08-24
- Target Recruit Count
- 295
- Registration Number
- NCT03596151
- Locations
- 🇺🇸
Magee Women's Hospital of UPMC - Reproductive Infectious Disease Research, Pittsburgh, Pennsylvania, United States
🇺🇸San Francisco Department of Public Health - San Francisco City Clinic, San Francisco, California, United States
🇺🇸Florida International University - Student Health Center, Miami, Florida, United States
Evaluating the Safety of and Adherence to a Vaginal Matrix Ring Containing Dapivirine and Oral Emtricitabine/Tenofovir Disoproxil Fumarate in an Adolescent and Young Adult Female Population
- Conditions
- HIV Infections
- Interventions
- Device: Dapivirine vaginal ringDrug: FTC/TDF
- First Posted Date
- 2018-07-20
- Last Posted Date
- 2023-06-22
- Target Recruit Count
- 247
- Registration Number
- NCT03593655
- Locations
- 🇺🇬
MU-JHU Research Collaboration (MUJHU CARE LTD) CRS, Kampala, Uganda
🇿🇼Spilhaus CRS, Southerton, Harare, Zimbabwe
🇿🇦Emavundleni CRS, Cape Town, Western Cape, South Africa
2013/2017 H7N9 Prime-Boost Interval
- Conditions
- Avian InfluenzaInfluenza Immunisation
- Interventions
- Biological: A/H7N9Drug: AS03Biological: Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013Other: Phosphate Buffered Saline (PBS) diluent
- First Posted Date
- 2018-07-18
- Last Posted Date
- 2021-08-02
- Target Recruit Count
- 180
- Registration Number
- NCT03589807
- Locations
- 🇺🇸
Emory Vaccine Center - The Hope Clinic, Decatur, Georgia, United States
🇺🇸Emory Children's Center - Pediatric Infectious Diseases, Atlanta, Georgia, United States
🇺🇸Saint Louis University - Center for Vaccine Development, Saint Louis, Missouri, United States