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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Pharmacokinetic/Pharmacodynamic Study of Oseltamivir in Immunocompromised Children With Confirmed Influenza Infection

Phase 1
Completed
Conditions
Influenza
Interventions
First Posted Date
2012-10-29
Last Posted Date
2018-10-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
20
Registration Number
NCT01715909
Locations
🇺🇸

Lucile Packard Child Hosp; Pediatric Pulmonary Division, Palo Alto, California, United States

🇧🇪

Cliniques Universitaires St-Luc, Bruxelles, Belgium

🇧🇷

Hospital São Lucas da PUCRS, Porto Alegre, RS, Brazil

and more 47 locations

A Study on The Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities

Phase 3
Completed
Conditions
Cardiovascular Disease, Diabetes Mellitus Type 2
Interventions
Drug: Placebo
First Posted Date
2012-10-29
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1999
Registration Number
NCT01715818

A Long-term Safety Extension Study of Tocilizumab in Brazilian Participants With Rheumatoid Arthritis (RA) Who Completed the Studies ML21530 and MA21488

Phase 4
Completed
Conditions
Arthritis, Rheumatoid
Interventions
First Posted Date
2012-10-29
Last Posted Date
2017-06-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
26
Registration Number
NCT01715831
Locations
🇧🇷

Hospital Universitario Cassiano Antonio Moraes - UFES; Reumatologia, Vitoria, ES, Brazil

🇧🇷

Centro Mineiro de Pesquisa - CMIP, Juiz de Fora, MG, Brazil

🇧🇷

Universidade Federal de Sao Paulo - UNIFESP; Reumatologia, Sao Paulo, SP, Brazil

and more 6 locations

A Safety And Pharmacokinetic Study of Setrobuvir Alone and In Combination With Ritonavir-Boosted Danoprevir in Subjects With Mild Hepatic Impairment Compared to Healthy Controls

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-10-25
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
18
Registration Number
NCT01714154

An Observational Study of First-Line Bevacizumab (Avastin) With Fluoropyrimidine-Based Chemotherapy in Participants With Metastatic Colorectal Cancer

Completed
Conditions
Colorectal Cancer
Interventions
Drug: Chemotherapy
First Posted Date
2012-10-23
Last Posted Date
2018-07-31
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
351
Registration Number
NCT01712347
Locations
🇨🇳

Chang Gung Medical Foundation - Chai Yi; Surgery, Chai Yi, Taiwan

🇨🇳

Kaohsiung Chang Gung Memorial Hospital; Colorectal Surgery, Kaohsiung, Taiwan

🇨🇳

National Cheng Kung Uni Hospital; Dept of Hematology and Oncology, Tainan, Taiwan

and more 6 locations

A Pharmacokinetic Study of Aleglitazar in Healthy Chinese Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-10-22
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
16
Registration Number
NCT01711775

A Study of Safety, Pharmacokinetics (Including Food Effect) And Pharmacodynamics of RO5545965 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2012-10-22
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
53
Registration Number
NCT01711801

A Study of the Combination of Multiple Doses of RO5285119 With a Single Dose of Risperidone in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-10-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
24
Registration Number
NCT01708616

An Observational Study of CellCept (Mycophenolate Mofetil) in Renal Allograft Recipients

Completed
Conditions
Kidney Transplantation
First Posted Date
2012-10-16
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
414
Registration Number
NCT01707550

A Study of Pegasys (Peginterferon Alfa-2a) Added to Nucleos(t)Ide Analogue Treatment in Participants With HBeAg-Negative Chronic Hepatitis B Genotype D Showing Stable Hepatitis B Virus (HBV) Deoxyribonucleic Acid (DNA) Suppression

Phase 2
Completed
Conditions
Hepatitis B, Chronic
Interventions
Drug: Pegylated Interferon (Peginterferon) Alfa-2a
Drug: Nucleos(t)ide Analogues (NA)
First Posted Date
2012-10-15
Last Posted Date
2017-02-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
76
Registration Number
NCT01706575
Locations
🇮🇹

A.O. Universitaria S. Maria Della Misericordia Di Udine; Oncologia; Clinica Medica, Udine, Friuli-Venezia Giulia, Italy

🇮🇹

Policlinico Umberto I Di Roma, Roma, Lazio, Italy

🇮🇹

Fondazione IRCCS Ospedale Maggiore Policlinico; Gastroenterologia, Milano, Lombardia, Italy

and more 10 locations
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