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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Non-Interventional Study of Rheumatoid Arthritis Patients Treated With RoActemra/Actemra (Tocilizumab) in Monotherapy

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2012-10-12
Last Posted Date
2018-09-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
71
Registration Number
NCT01705730
Locations
🇧🇪

CH EpiCURA Site Ath, Ath, Belgium

🇧🇪

CHU Brugmann (Victor Horta), Bruxelles, Belgium

🇧🇪

ASZ Aalst, Aalst, Belgium

and more 14 locations

A Retrospective Biomarker Study of Stored Samples Obtained From Patients With Chronic Hepatitis B

Completed
Conditions
Hepatitis B, Chronic
First Posted Date
2012-10-12
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
269
Registration Number
NCT01705704

A Retrospective Study of Real World Treatment Outcomes of Patients With Chronic Hepatitis C

Completed
Conditions
Hepatitis C, Chronic
First Posted Date
2012-10-12
Last Posted Date
2017-04-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
49
Registration Number
NCT01705717
Locations
🇹🇭

Faculty of Medicine Vajira Hospital; Division of Gastroenterology and Hepatology, Bangkok, Thailand

A Combination Study of Kadcyla (Trastuzumab Emtansine) and Capecitabine in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer (mBC) or HER2-Positive Locally Advanced/Metastatic Gastric Cancer (LA/mGC)

Phase 2
Terminated
Conditions
Breast Cancer
Gastric Cancer
Interventions
First Posted Date
2012-10-08
Last Posted Date
2021-01-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
182
Registration Number
NCT01702558
Locations
🇧🇷

Hospital Erasto Gaertner, Curitiba, PR, Brazil

🇧🇷

Instituto Oncologico de Ribeirao Preto - INORP, Ribeirao Preto, SP, Brazil

🇧🇷

Faculdade de Medicina de Sao Jose do Rio Preto - FAMERP*X*, Sao Jose do Rio Preto, SP, Brazil

and more 37 locations

A Study of Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer Who Have Received Prior Anti-HER2 And Chemotherapy-based Treatment

Phase 3
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2012-10-08
Last Posted Date
2022-04-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
2185
Registration Number
NCT01702571
Locations
🇦🇺

Mater Hospital; Patricia Ritchie Centre for Cancer Care and Research, North Sydney, New South Wales, Australia

🇦🇷

CEMIC, Buenos Aires, Argentina

🇧🇪

CHU Sart-Tilman, Liège, Belgium

and more 297 locations

A Pharmacokinetics Study of Aleglitazar in Combination With Digoxin in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-10-05
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
28
Registration Number
NCT01701739

A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer, Alzheimer's Disease
Interventions
Drug: 11C-L-deprenyl-D2
First Posted Date
2012-10-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
17
Registration Number
NCT01701089

A Bioequivalence Study of an Oral Solution of Copegus (Ribavirin) Compared to Copegus Tablets

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-10-02
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT01697436

A Study Evaluating IL28B Polymorphism in Patients With HBeAg-Negative Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a) in Study ML18253

Phase 3
Completed
Conditions
Hepatitis B, Chronic
Interventions
Other: Interleukin 28B testing
First Posted Date
2012-10-02
Last Posted Date
2017-04-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
88
Registration Number
NCT01697501
Locations
🇮🇹

Fondazione IRCCS Ospedale Maggiore Policlinico; Gastroenterologia, Milano, Lombardia, Italy

🇮🇹

Azienda Ospedaliera Policlinico Consorziale di Bari; Clinica Malattie Infettive, Bari, Puglia, Italy

🇮🇹

Uni Di Cagliari; Dept. Di Scienze Mediche, Cagliari, Sardegna, Italy

and more 9 locations
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