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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study Comparing Vemurafenib Versus Vemurafenib Plus Cobimetinib in Participants With Metastatic Melanoma

Phase 3
Completed
Conditions
Malignant Melanoma
Interventions
First Posted Date
2012-09-21
Last Posted Date
2022-05-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
495
Registration Number
NCT01689519
Locations
🇧🇪

UZ Antwerpen, Edegem, Belgium

🇬🇧

Velindre Cancer Centre, Cardiff, United Kingdom

🇦🇺

Lismore Base Hospital; Cancer Care & Haematology Unit, Lismore, New South Wales, Australia

and more 153 locations

A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Phase 1
Completed
Conditions
Neoplasms
Interventions
Biological: Atezolizumab [TECENTRIQ]
Biological: Vanucizumab
First Posted Date
2012-09-19
Last Posted Date
2018-10-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
132
Registration Number
NCT01688206
Locations
🇧🇪

UZ Leuven Gasthuisberg, Leuven, Belgium

🇧🇪

Cliniques Universitaires St-Luc, Bruxelles, Belgium

🇫🇷

Centre Francois Baclesse; Oncologie, Caen, France

and more 11 locations

A 28-Day Pharmacokinetics Study of RG1662 in Healthy Male Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-09-13
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
6
Registration Number
NCT01684891

An Observational Study of First-Line Maintenance Rituximab (MabThera/Rituxan) in Participants With Follicular Non-Hodgkin's Lymphoma

Completed
Conditions
Non-Hodgkin's Lymphoma
Interventions
First Posted Date
2012-09-13
Last Posted Date
2017-12-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
22
Registration Number
NCT01684865
Locations
🇲🇰

University Clinic of Hematology Skopje, Hospital Care Department, Skopje, Macedonia, The Former Yugoslav Republic of

Pertuzumab in Platinum-Resistant Low Human Epidermal Growth Factor Receptor 3 (HER3) Messenger Ribonucleic Acid (mRNA) Epithelial Ovarian Cancer (PENELOPE)

First Posted Date
2012-09-13
Last Posted Date
2017-05-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
208
Registration Number
NCT01684878
Locations
🇳🇱

Academ Ziekenhuis Groningen; Medical Oncology, Groningen, Netherlands

🇳🇱

Academisch Ziekenhuis Leiden; Clinical Oncology, Leiden, Netherlands

🇳🇱

UMC St Radboud, Nijmegen, Netherlands

and more 65 locations

Observational Study of Tocilizumab in Participants With Rheumatoid Arthritis in Australia

Completed
Conditions
Rheumatoid Arthritis
Interventions
Other: Observational study
First Posted Date
2012-09-12
Last Posted Date
2016-07-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
37
Registration Number
NCT01683604

A Study of Obinutuzumab in Chinese Participants With CD20+ Malignant Disease

Phase 1
Completed
Conditions
Lymphocytic Leukemia, Chronic, Diffuse Large B-cell Lymphoma, Follicular Lymphoma
Interventions
First Posted Date
2012-09-07
Last Posted Date
2016-04-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
48
Registration Number
NCT01680991

A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease

Phase 2
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
Drug: placebo
First Posted Date
2012-09-07
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
18
Registration Number
NCT01680978

A Study to Investigate the Effects of Rifampicin on the Pharmacokinetics of Aleglitazar in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-09-06
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
24
Registration Number
NCT01679639

An Observational Study of Pegasys in Dual- or Triple-Therapy in Patients With Chronic Hepatitis C

Completed
Conditions
Hepatitis C, Chronic
First Posted Date
2012-09-06
Last Posted Date
2018-03-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
7500
Registration Number
NCT01679834
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