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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

An Observational Study of Tarceva (Erlotinib) in Elderly Patients With Advanced Non-Small Cell Lung Cancer

Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
First Posted Date
2012-02-20
Last Posted Date
2015-10-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
465
Registration Number
NCT01535729

A Study of RoActemra/Actemra (Tocilizumab) Versus Placebo in Patients With Systemic Sclerosis

Phase 3
Completed
Conditions
Sclerosis, Systemic
Interventions
First Posted Date
2012-02-15
Last Posted Date
2016-09-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
87
Registration Number
NCT01532869

A Study of Drug-Drug Interaction Between Danoprevir/Low-Dose Ritonavir and Raltegravir in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-02-13
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
20
Registration Number
NCT01531647

A Study of Vemurafenib in Participants With BRAF V600 Mutation-Positive Cancers

Phase 2
Completed
Conditions
Multiple Myeloma, Neoplasms
Interventions
First Posted Date
2012-02-02
Last Posted Date
2017-11-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
208
Registration Number
NCT01524978
Locations
🇫🇷

Centre Georges François Leclerc, Dijon, France

🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

🇺🇸

Arizona Oncology, Tucson, Arizona, United States

and more 31 locations

A Study of The Effect of Altitude on Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) Dose Requirements in Participants With Chronic Renal Anemia in Pre-Dialysis or Dialysis

Phase 4
Completed
Conditions
Anemia, Kidney Disease, Chronic
Interventions
First Posted Date
2012-01-27
Last Posted Date
2019-06-19
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
87
Registration Number
NCT01519947
Locations
🇲🇽

Unidad De Dialisis La Loma S.C., Pureto Vallarta, Mexico

🇲🇽

Clínica San Cosme Centro Especializado en el Tratamiento de Enfermedades Renales S.C, Aguascalientes, Mexico

🇲🇽

Nefros Investigación S.C., Delegación Coyoacan, Mexico

and more 4 locations

A Study of Pegasys (Peginterferon Alfa-2a) Versus Untreated Control in Children With HBeAg Positive Chronic Hepatitis B

Phase 3
Completed
Conditions
Hepatitis B, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2012-01-27
Last Posted Date
2022-11-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
165
Registration Number
NCT01519960
Locations
🇺🇸

Johns Hopkins Hospital - Pediatric Gastroenterology, Baltimore, Maryland, United States

🇺🇸

Children's Hospital Boston-Harvard Medical School; Division of Gastoenterology, Boston, Massachusetts, United States

🇺🇸

Seattle Children's Hospital, Seattle, Washington, United States

and more 36 locations

A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With HBeAg Positive Chronic Hepatitis B.

Phase 4
Completed
Conditions
Hepatitis B, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2012-01-27
Last Posted Date
2016-04-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
150
Registration Number
NCT01519921

BRIM-P: A Study of Vemurafenib in Pediatric Patients With Stage IIIC or Stage IV Melanoma Harboring BRAFV600 Mutations

Phase 1
Terminated
Conditions
Malignant Melanoma
Interventions
First Posted Date
2012-01-26
Last Posted Date
2016-10-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
6
Registration Number
NCT01519323

A Study of Drug-Drug Interaction Between Darunavir and Danoprevir Administered Together With Low-Dose Ritonavir in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-01-26
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT01519336

A Study of RO4917523 in Patients With Fragile X Syndrome

Phase 2
Completed
Conditions
Fragile X Syndrome
Interventions
Drug: RO4917523 0.5 mg
Drug: RO4917523 1.5 mg
Drug: Placebo
First Posted Date
2012-01-25
Last Posted Date
2016-07-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
185
Registration Number
NCT01517698
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