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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study on the Effects of Valproate on the Pharmacokinetics of RO4917838 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-12-19
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
18
Registration Number
NCT01495104

A Study of RO5093151 in Patients With Ocular Hypertension Or Open Angle Glaucoma

Phase 2
Completed
Conditions
Hypertension, Glaucoma, Open-Angle
Interventions
Drug: Placebo
First Posted Date
2011-12-15
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
31
Registration Number
NCT01493271

A Study of Capecitabine Rapid Disintegrating Tablets (RDT) Versus Commercial Xeloda in Patients With Solid Tumours

Phase 1
Completed
Conditions
Breast Cancer, Colorectal Cancer
Interventions
First Posted Date
2011-12-15
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
37
Registration Number
NCT01493336

A Study of Pertuzumab in Combination With Trastuzumab Plus an Aromatase Inhibitor in Participants With Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive and Hormone Receptor-Positive Advanced Breast Cancer

Phase 2
Completed
Conditions
Breast Cancer
Interventions
Drug: Aromatase Inhibitor
Drug: Induction Chemotherapy
First Posted Date
2011-12-14
Last Posted Date
2020-10-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
258
Registration Number
NCT01491737
Locations
🇹🇷

Ankara City Hospital, Ankara, Turkey

🇺🇸

Washington University School of Medicine; Internal Medicine - Renal, Saint Louis, Missouri, United States

🇺🇸

Ironwood Cancer TX & Rsch Ctrs, Chandler, Arizona, United States

and more 79 locations

An Observational Study of Tarceva (Erlotinib) in Patients With Non-Small Cell Lung Cancer

Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
First Posted Date
2011-12-08
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
217
Registration Number
NCT01488331

An Observational Study of MabThera/Rituxan (Rituximab) in Patients With Relapsing or Refractory Chronic Lymphocytic Leukemia

Completed
Conditions
Lymphocytic Leukemia, Chronic
First Posted Date
2011-12-08
Last Posted Date
2017-03-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
327
Registration Number
NCT01488162

An Observational Study to Register the Incidence of Breast Cancer and Current Clinical Care Patterns in Kenya

Completed
Conditions
Breast Cancer
First Posted Date
2011-12-02
Last Posted Date
2019-12-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
400
Registration Number
NCT01484483
Locations
🇰🇪

University of Nairobi School of Medicine; Internal Medicine and Therapeutics, Nairobi, Kenya

A Study of Ritonavir-Boosted Danoprevir and RO5024048 in Different Combinations in Null Responder or Treatment-Naïve Patients With Chronic Hepatitis C and Compensated Cirrhosis

Phase 2
Completed
Conditions
Hepatitis C, Chronic
Interventions
First Posted Date
2011-12-01
Last Posted Date
2016-08-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
43
Registration Number
NCT01483742

Evaluation of Accu-Chek DiaPort, a Port System for Continuous Intraperitoneal Insulin Infusion, in Patients With Type I Diabetes

Not Applicable
Completed
Conditions
Diabetes Mellitus, Type 1
Interventions
Device: Accu-Chek DiaPort
First Posted Date
2011-12-01
Last Posted Date
2016-04-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
12
Registration Number
NCT01483352

A Relative Bioavailability Study of Danoprevir and Ritonavir in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-12-01
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
36
Registration Number
NCT01483729
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