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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

An Observational Study on Long-Term Efficacy and Safety of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis (FAct)

Completed
Conditions
Rheumatoid Arthritis
First Posted Date
2011-12-01
Last Posted Date
2019-05-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
215
Registration Number
NCT01483326
Locations
🇳🇱

Scheper Ziekenhuis, Emmen, Netherlands

🇳🇱

Amphia ziekenhuis, locatie langendijk, Breda, Netherlands

🇳🇱

Medisch Centrum Twente; Rheumatology, Enschede, Netherlands

and more 16 locations

A Human Proof of Concept Study for [11C]-RO5011232 as Radiotracer and Study of the Binding of RO4917523 to Human mGlu5 Brain Receptor at Steady-State in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: RO5011232
First Posted Date
2011-12-01
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
56
Registration Number
NCT01483469

A Study of Mericitabine in Combination With Boceprevir and Pegasys/Copegus in Patients With Chronic Hepatitis C

First Posted Date
2011-11-30
Last Posted Date
2016-08-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
58
Registration Number
NCT01482403

A Study of RO5479599 Alone or in Combination With Cetuximab or Erlotinib in Participants With Metastatic and/or Locally Advanced Malignant Human Epidermal Growth Factor Receptor (HER3) Expressing Solid Tumors of Epithelial Cell Origin

Phase 1
Completed
Conditions
Neoplasms
Interventions
Drug: zirconium-89-labeled RO5479599
First Posted Date
2011-11-30
Last Posted Date
2017-01-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
145
Registration Number
NCT01482377
Locations
🇳🇱

Academ Ziekenhuis Groningen; Medical Oncology, Groningen, Netherlands

🇰🇷

National Cancer Center, Gyeonggi-do, Korea, Republic of

🇳🇱

Antoni van Leeuwenhoek Ziekenhuis, Amsterdam, Netherlands

and more 9 locations

A Study of Mericitabine in Combination With Telaprevir and Peginterferon Alfa-2a / Ribavirin in Participants With Chronic Hepatitis C

Phase 2
Completed
Conditions
Hepatitis C
Interventions
First Posted Date
2011-11-30
Last Posted Date
2017-04-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
80
Registration Number
NCT01482390
Locations
🇺🇸

Carolina'S Center For Liver Disease, Statesville, North Carolina, United States

🇺🇸

Harborview Medical Center, Seattle, Washington, United States

🇺🇸

Birmingham Gastro Associates, P.C., Birmingham, Alabama, United States

and more 36 locations

An Observational Study of Patients With HER2-Positive Metastatic or Locally Advanced Breast Cancer Treated With Herceptin (Trastuzumab) in 1st Line and Without Progression For 3 Years

Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2011-11-29
Last Posted Date
2017-08-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
160
Registration Number
NCT01480674
Locations
🇫🇷

Ch De Brive La Gaillarde; Radiotherapie Oncologie, Brive La Gaillarde, France

🇫🇷

Ch William Morey; Medecine 1, Chalon Sur Saone, France

🇫🇷

Centre Jean Perrin; Hopital De Jour, Clermont Ferrand, France

and more 75 locations

A Study of the Metabolic Profile of Dalcetrapib in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-11-22
Last Posted Date
2019-12-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
6
Registration Number
NCT01476267

A Study of RO5028442 in Adult Male High-Functioning Autistic Patients

Phase 1
Completed
Conditions
Autistic Disorder
Interventions
Drug: Placebo
First Posted Date
2011-11-18
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
19
Registration Number
NCT01474278

A Study of Avastin (Bevacizumab) And Fotemustine in Patients With Recurrent Glioblastoma

Phase 2
Completed
Conditions
Glioblastoma Multiforme
Interventions
First Posted Date
2011-11-18
Last Posted Date
2016-03-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
91
Registration Number
NCT01474239

An Observational Study of RoActemra/Actemra (Tocilizumab) As Monotherapy in Rheumatoid Arthritis Patients in Routine Clinical Practice

Completed
Conditions
Rheumatoid Arthritis
Interventions
Biological: Tocilizumab
First Posted Date
2011-11-18
Last Posted Date
2016-10-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
608
Registration Number
NCT01474291
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