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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study in Patients With Moderate to Severe Active Rheumatoid Arthritis Comparing Different Infusion Durations of RoActemra/Actemra (Tocilizumab) Treatment

Phase 2
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2011-11-09
Last Posted Date
2015-08-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
47
Registration Number
NCT01468077

A First-In-Human Study of RO5503781 in Participants With Advanced Malignancies Except Leukemia

Phase 1
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2011-10-31
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
99
Registration Number
NCT01462175

A Prospective Observational Study of Tocilizumab (RoActemra/Actemra) in Participants With Rheumatoid Arthritis

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2011-10-31
Last Posted Date
2016-10-31
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
122
Registration Number
NCT01462162

A Study Comparing Maintenance Subcutaneous Rituximab With Observation Only in Participants With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma Who Had Responded to Rituximab-based Immunochemotherapy Induction and 2-year Maintenance With Subcutaneous Rituximab

Phase 3
Completed
Conditions
Non-Hodgkin's Lymphoma
Interventions
Drug: Chemotherapy (Induction Period)
First Posted Date
2011-10-28
Last Posted Date
2019-08-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
692
Registration Number
NCT01461928
Locations
🇧🇬

Tokuda Hospital Sofia; Hematology department, Sofia, Bulgaria

🇦🇹

Medizinische Universität Wien; Univ.Klinik für Innere Medizin I - Hämatologie & Hämostaseologie, Wien, Austria

🇨🇴

Instituto Nacional de Cancerologia; Hematology, Bogota, Colombia

and more 177 locations

A Study on Safety, Pharmacokinetics and Pharmacodynamics of RO5508887 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2011-10-28
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
49
Registration Number
NCT01461967

A Study of Pertuzumab in Combination With Trastuzumab and Chemotherapy in Patients With HER2-Positive Advanced Gastric Cancer

Phase 2
Completed
Conditions
Gastric Cancer
Interventions
First Posted Date
2011-10-27
Last Posted Date
2018-08-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
30
Registration Number
NCT01461057
Locations
🇨🇿

Fakultni nemocnice Olomouc; Onkologicka klinika, Olomouc, Czechia

🇧🇪

UZ Leuven Gasthuisberg, Leuven, Belgium

🇮🇹

Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 2, Milano, Lombardia, Italy

and more 21 locations

An Observational Study of Avastin (Bevacizumab) in Patients With HER2-metastatic or Locally Advanced Breast Cancer

Completed
Conditions
Breast Cancer
First Posted Date
2011-10-27
Last Posted Date
2016-01-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
228
Registration Number
NCT01461044

ACCU-CHEK® Aviva Expert Study: Does Use of a Bolus Advisor Improve Glycemic Control in Patients Not Achieving Optimal Control Using Multiple Daily Injections (MDI)?

Not Applicable
Completed
Conditions
Diabetes Mellitus, Type 2
Diabetes Mellitus, Type 1
Interventions
Device: Aviva Expert blood glucose meter
Device: Aviva Nano blood glucose meter
First Posted Date
2011-10-26
Last Posted Date
2014-02-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
218
Registration Number
NCT01460446

ARTDeCo Study: A Study of RO4995819 in Patients With Major Depressive Disorder And Inadequate Response to Ongoing Antidepressant Treatment

Phase 2
Completed
Conditions
Major Depressive Disorder
Interventions
Drug: Placebo
First Posted Date
2011-10-24
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
357
Registration Number
NCT01457677

A Study of RO4995819 in Healthy Elderly Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2011-10-24
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
30
Registration Number
NCT01457664
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