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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

An Observational Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) as Maintenance Treatment in Patients With Chronic Renal Anemia on Haemodialysis

Completed
Conditions
Anemia, Kidney Disease, Chronic
First Posted Date
2011-08-24
Last Posted Date
2016-03-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
185
Registration Number
NCT01422824

A Study of Trastuzumab Emtansine in Comparison With Treatment of Physician's Choice in Participants With HER2-positive Breast Cancer Who Have Received at Least Two Prior Regimens of HER2-directed Therapy

Phase 3
Completed
Conditions
Breast Cancer
Interventions
Drug: Treatment of physician's choice
First Posted Date
2011-08-18
Last Posted Date
2016-10-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
602
Registration Number
NCT01419197

A Study of RO5285119 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: placebo
First Posted Date
2011-08-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
77
Registration Number
NCT01418963

A Study to Evaluate the Effect of Danoprevir/Ritonavir on the Pharmacokinetics of Escitalopram and S-Demethylcitalopram in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-08-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
20
Registration Number
NCT01418274

A Study of Administration of RoActemra/Actemra (Tocilizumab) by Auto-injector Vs. Pre-filled Syringe in Healthy Volunteers

First Posted Date
2011-08-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
239
Registration Number
NCT01418989

An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Anemic Patients With Chronic Kidney Disease (NORM)

Completed
Conditions
Anemia
Interventions
First Posted Date
2011-08-16
Last Posted Date
2017-07-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
22
Registration Number
NCT01417377
Locations
🇵🇰

Fatima Memorial Hospital; Nephrology, Lahore, Pakistan

🇵🇰

Surgimed Hospital, Lahore, Pakistan

🇵🇰

Sheikh Zayed Hospital; Department of Nephrology, Lahore, Pakistan

and more 3 locations

An Observational Study of Pegasys (Peginterferon Alfa-2a) Plus Copegus (Ribavirin) in Participants With Chronic Hepatitis C (CHC), Genotype 2, 3, 1 or 4, Undergoing Opioid Maintenance Therapy

Completed
Conditions
Hepatitis C, Chronic
First Posted Date
2011-08-15
Last Posted Date
2017-04-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
88
Registration Number
NCT01416610
Locations
🇦🇹

Lkh-Univ. Klinikum Graz, Graz, Austria

🇦🇹

Lkh Hoergas-Enzenbach; Abt. Für Innere Medizin, Gratwein, Austria

🇦🇹

Lkh innsbruck - univ. Klinikum innsbruck - Tiroler landeskrankenanstalten ges.m.b.h.; Innere Medizin, Innsbruck, Austria

and more 7 locations

A Study of Ocrelizumab in Comparison With Interferon Beta-1a (Rebif) in Participants With Relapsing Multiple Sclerosis

Phase 3
Completed
Conditions
Relapsing Multiple Sclerosis
Interventions
Drug: Ocrelizumab-matching placebo
Drug: Interferon beta-1a-matching placebo
First Posted Date
2011-08-09
Last Posted Date
2024-03-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
835
Registration Number
NCT01412333
Locations
🇺🇸

Infinity Clinical Research, Hollywood, Florida, United States

🇺🇸

Stanford University Medical Center, Palo Alto, California, United States

🇺🇸

Advanced Neurosciences Research LLC, Fort Collins, Colorado, United States

and more 162 locations

A Study on The Effect of Multiple Doses of Activated Charcoal on The Pharmacokinetics of a Single Dose of RO4995819

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-08-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
26
Registration Number
NCT01409369

Participant Preference of Subcutaneous (SC) Versus Intravenous (IV) Herceptin (Trastuzumab) in Human Epidermal Growth Factor Receptor (HER) 2-Positive Early Breast Cancer

Phase 2
Completed
Conditions
Breast Neoplasms
Interventions
Device: Single-Use Injection Device
First Posted Date
2011-07-25
Last Posted Date
2017-03-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
488
Registration Number
NCT01401166
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