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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Translational Study of Bevacizumab in Participants With Metastatic Colorectal Cancer

Phase 4
Completed
Conditions
Colorectal Neoplasms
Interventions
First Posted Date
2012-05-01
Last Posted Date
2019-01-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
128
Registration Number
NCT01588990
Locations
🇦🇺

Calvary North Adelaide; North Adeliade Oncology Centre, North Adelaide, South Australia, Australia

🇦🇺

Canberra Hospital, Garran, Australian Capital Territory, Australia

🇦🇺

Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia

and more 14 locations

A Study of RoActemra/Actemra (Tocilizumab) With or Without Methotrexate in Patients With Mild to Moderate Rheumatoid Arthritis With an Inadequate Response to Methotrexate

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2012-04-30
Last Posted Date
2015-07-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
77
Registration Number
NCT01587989

A Study of Potential Drug-Drug Interaction Between Efavirenz and Danoprevir With Low Dose Ritonavir in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-04-30
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT01588002

An Extension Study to Provide Continued Bevacizumab Therapy to Participants With Solid Tumors Who Were Previously Enrolled in a Roche/Genentech Sponsored Study

Phase 4
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2012-04-30
Last Posted Date
2020-11-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
95
Registration Number
NCT01588184
Locations
🇦🇹

A.Ö. LKH; Abt. für Lungenkrankheiten, Steyr, Austria

🇧🇷

Hospital Perola Byington, Sao Paulo, SP, Brazil

🇧🇷

Hospital A. C. Camargo; Oncologia, Sao Paulo, SP, Brazil

and more 70 locations

A Study of The Relationship Between Drop in Hemoglobin and Sustained Virological Response in Patients With Chronic Hepatitis C Treated With Copegus (Ribavirin) and Pegasys (Peginterferon Alfa-2a)

Phase 4
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2012-04-25
Last Posted Date
2015-07-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
30
Registration Number
NCT01585324

A Non-Drug Study of The Suitability of Neurocognitive Tests And Functioning Scales For The Measurement of Cognitive And Functioning Changes in Individuals With Down Syndrome

Completed
Conditions
Down Syndrome
First Posted Date
2012-04-19
Last Posted Date
2015-03-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
90
Registration Number
NCT01580384

Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2012-04-17
Last Posted Date
2016-03-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
184
Registration Number
NCT01579006

A Study of RO5024048 in Combination With Ritonavir-Boosted Danoprevir and Pegasys/Copegus in Patients With Chronic Hepatitis C Genotype 1 Who Have Failed Prior HCV Protease Inhibitor Treatment

Phase 2
Withdrawn
Conditions
Hepatitis C, Chronic
Interventions
First Posted Date
2012-04-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT01579019

An Extension Study to WA19977 in Patients With Active Polyarticular-Course Juvenile Idiopathic Arthritis

Phase 3
Terminated
Conditions
Juvenile Idiopathic Arthritis
Interventions
Drug: RoActemra/Actemra (tocilizumab)
First Posted Date
2012-04-11
Last Posted Date
2018-02-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
41
Registration Number
NCT01575769
Locations
🇵🇱

Wojewodzki Szpital Dzieciecy Im. J. Brudzinskiego, Bydgoszcz, Poland

🇷🇺

SI Sceintific children health center RAMS, Moscow, Russian Federation

🇷🇺

GOU VPO Rostovskiy state medical university Roszdrav, Rostov-na-donu, Russian Federation

and more 8 locations

A Study of Pertuzumab in Combination With Trastuzumab (Herceptin) and a Taxane in First-Line Treatment in Participants With Human Epidermal Growth Factor 2 (HER2)-Positive Advanced Breast Cancer

First Posted Date
2012-04-05
Last Posted Date
2020-09-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1436
Registration Number
NCT01572038
Locations
🇦🇷

Centro Oncologico Riojano Integral (CORI), La Rioja, Argentina

🇦🇹

LKH-UNIV. KLINIKUM GRAZ; Klinische Abteilung für Onkologie, Graz, Austria

🇧🇪

UZ Brussel, Brussel, Belgium

and more 296 locations
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