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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of RO5045337 in Combination With Doxorubicin in Patients With Soft Tissue Sarcoma

Phase 1
Completed
Conditions
Sarcoma
Interventions
First Posted Date
2012-05-25
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
23
Registration Number
NCT01605526

An Observational Study of Dual and Triple Therapies Based on Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis C

Completed
Conditions
Hepatitis C, Chronic
First Posted Date
2012-05-23
Last Posted Date
2019-03-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
991
Registration Number
NCT01604291
Locations
🇮🇱

Tel-Aviv Sourasky Medical Center; Liver Unit, Tel Aviv, Israel

🇮🇱

Haemek Hospital; Gastroenterology, Afula, Israel

🇮🇱

Barzilai MC; Gastroenterology, Ashkelon, Israel

and more 18 locations

A Pharmacodynamic and Pharmacokinetic Study of RO5508887 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2012-05-07
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
42
Registration Number
NCT01592331

An Observational Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis And Inadequate Response Or Intolerance to a First Anti-TNF Alpha Therapy

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2012-05-07
Last Posted Date
2016-08-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
90
Registration Number
NCT01592292

A Study of The Excretion Balance, Pharmacokinetics and Metabolism of A Single Oral Dose of [14C]-Labeled RO4917523 in Healthy Male Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-05-07
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
6
Registration Number
NCT01592890

A Study of Drug-Drug Interaction Between Danoprevir Coadministered With Low-Dose Ritonavir and Tenofovir Disoproxil Fumarate or Atazanavir

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-05-07
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT01592305

A Study of The Relative Bioavailability of Ritonavir-Boosted Danoprevir Fixed Dose Combination Tablets in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-05-07
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
42
Registration Number
NCT01592318

A Drug-Drug Interaction Study of Ketoconazole, Rifampicin and Ritonavir-Boosted Atazanavir With Single-Dose RO5093151 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-05-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
51
Registration Number
NCT01591850

A Triple Combination Therapy Study of Boceprevir, Pegasys and Copegus in Previously Untreated Patients With Genotype 1 Chronic Hepatitis C

Phase 4
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2012-05-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
165
Registration Number
NCT01591460
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