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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of the Effect of RO4917838 on the QTcF Interval in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: RO4917838 placebo
First Posted Date
2012-06-06
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
169
Registration Number
NCT01613040

An Observational Study of MabThera in Participants With Severe Active Rheumatoid Arthritis

Completed
Conditions
Rheumatoid Arthritis
Interventions
Biological: Rituximab
First Posted Date
2012-06-06
Last Posted Date
2016-10-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
135
Registration Number
NCT01613027

A Relative Bioavailability Study of Setrobuvir Tablet Formulation Versus Reference Setrobuvir Capsule Formulation in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-06-05
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT01612143

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs (REMISSION)

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2012-06-04
Last Posted Date
2014-07-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
121
Registration Number
NCT01610791

A Study of Tarceva (Erlotinib) in First Line in Patients With Locally Advanced or Metastatic Lung Adenocarcinoma With EGFR Mutations

Phase 4
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2012-06-01
Last Posted Date
2016-02-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
62
Registration Number
NCT01609543

An Observational Study of Peginterferon Alfa-2a in Combination With Ribavirin in Participants With Chronic Hepatitis C and Compensated Liver Cirrhosis

Completed
Conditions
Hepatitis C, Chronic
Interventions
First Posted Date
2012-05-31
Last Posted Date
2017-04-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1496
Registration Number
NCT01609049
Locations
🇷🇺

Kirov Region Aids-Center; Infectious, Kirov, Russian Federation

🇷🇺

Infections Deseases Hospital #1, Novosibirsk, Russian Federation

🇷🇺

Krasnoyarsk Region Aids Center; Hepatology, Krasnoyarsk, Russian Federation

and more 54 locations

A Study of Rituximab (MabThera) in Combination With Chemotherapy in Participants With CD20-Positive B-Cell Chronic Lymphocytic Leukemia

Completed
Conditions
Lymphocytic Leukemia, Chronic
Interventions
First Posted Date
2012-05-31
Last Posted Date
2018-06-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
67
Registration Number
NCT01609023
Locations
🇬🇷

Metropolitan Hospital; Hematology Dept, Athens, Greece

🇬🇷

University Hospital of Larissa; Hematology Dept., Larissa, Greece

🇬🇷

Laiko General Hospital of Athens; A Propedeutical Clinic of Internal Medicine, Athens, Greece

and more 6 locations

An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer in Italy (BEWARE)

Completed
Conditions
Colorectal Cancer
First Posted Date
2012-05-31
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
437
Registration Number
NCT01609075

A Study of MabThera/Rituxan (Rituximab) Alone and in Combination With Roferon-A in Patients With Follicular or Other CD20+ Low-Grade (Indolent) Lymphoma

Phase 3
Completed
Conditions
Lymphoma
Interventions
Drug: interferon-a-2a
First Posted Date
2012-05-31
Last Posted Date
2014-09-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
313
Registration Number
NCT01609010

An Observational Study of MabThera/Rituxan (Rituximab) in Patients With Follicular Lymphoma

Terminated
Conditions
Lymphoma, Follicular
First Posted Date
2012-05-31
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
3
Registration Number
NCT01609036
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