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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

An Observational Study of MabThera/Rituxan (Rituximab) in Patients With Rheumatoid Arthritis and an Inadequate Response or Intolerance to One Anti-Tumor Necrosis Factor (Anti-TNF) Agent

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2012-07-17
Last Posted Date
2016-08-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
505
Registration Number
NCT01641952

A Study of RO5429083 Alone or in Combination With Cytarabine in Patients With Acute Myelogenous Leukemia

Phase 1
Completed
Conditions
Myelogenous Leukemia, Acute
Interventions
Drug: RO5429083
First Posted Date
2012-07-16
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
44
Registration Number
NCT01641250

A Retrospective Chart Review on the Use of Biologics in Monotherapy for the Treatment of Patients With Rheumatoid Arthritis

Completed
Conditions
Rheumatoid Arthritis
First Posted Date
2012-07-13
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
320
Registration Number
NCT01640548

A Study of Ritonavir-Boosted Invirase (Saquinavir) in Treatment-Naïve HIV-1 Infected Patients

Phase 1
Completed
Conditions
HIV Infections
Interventions
Drug: Nucleoside Reverse Transcriptase Inhibitor (NRTIs)
First Posted Date
2012-07-12
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
23
Registration Number
NCT01638650

A Study of A High Concentration Liquid Formulation Versus A Lyophilized Formulation of Gantenerumab in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-07-10
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
120
Registration Number
NCT01636531

A Study of Bitopertin (RO4917838) in Healthy Male Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: placebo
First Posted Date
2012-07-10
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
71
Registration Number
NCT01636492

A Study of RO5045337 in Combination With Cytarabine in Patients With Acute Myelogenous Leukemia

Phase 1
Completed
Conditions
Myelogenous Leukemia, Acute
Interventions
First Posted Date
2012-07-09
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
43
Registration Number
NCT01635296

An Non-Interventional Study of Patients With Persistent Symptoms of Schizophrenia

Completed
Conditions
Schizophrenia
First Posted Date
2012-07-06
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1433
Registration Number
NCT01634542

A Study of Onartuzumab (MetMAb) in Combination With Bevacizumab Compared to Bevacizumab Alone or Onartuzumab Monotherapy in Participants With Recurrent Glioblastoma

Phase 2
Completed
Conditions
Glioblastoma
Interventions
First Posted Date
2012-07-02
Last Posted Date
2018-02-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
135
Registration Number
NCT01632228
Locations
🇩🇪

Ärztehaus Velen, Ibbenbühren, Germany

🇨🇦

McGill University; Montreal Neurological Institute; Oncology, Montreal, Quebec, Canada

🇨🇦

London Health Sciences Centre, London, Ontario, Canada

and more 59 locations

A Single Dose Study of Radiolabeled RO4602522 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-06-29
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
6
Registration Number
NCT01631422
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