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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

An Observational Study in Clinical Practice Management of Patients With Biological Drugs in Monotherapy

Completed
Conditions
Rheumatoid Arthritis
First Posted Date
2012-08-14
Last Posted Date
2016-04-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
210
Registration Number
NCT01664117

An Observational Study of Erlotinib (Tarceva) as Second-line Treatment in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer After Failure of Pemetrexed in First-line Therapy

Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2012-08-14
Last Posted Date
2015-12-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
57
Registration Number
NCT01664533

A Single-Center Study of RO5508887 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2012-08-14
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
36
Registration Number
NCT01664143

An Observational Study of Xeloda (Capecitabine) in Patients With Metastatic Colorectal Cancer, Colon Cancer in the Adjuvant Setting, Advanced Gastric Cancer or Breast Cancer

Completed
Conditions
Breast Cancer, Colorectal Cancer, Gastric Cancer
Interventions
First Posted Date
2012-08-14
Last Posted Date
2016-05-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
563
Registration Number
NCT01664494

Study To Evaluate the Efficacy and Safety Of Bevacizumab, and Associated Biomarkers, In Combination With Paclitaxel Compared With Paclitaxel Plus Placebo as First-line Treatment Of Patients With Her2-Negative Metastatic Breast Cancer

Phase 3
Completed
Conditions
Metastatic Breast Cancer
Interventions
First Posted Date
2012-08-13
Last Posted Date
2019-01-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
481
Registration Number
NCT01663727
Locations
🇺🇸

Univ of Texas Medical Branch, Galveston, Texas, United States

🇺🇸

Texas Oncology, P.A., The Woodlands, Texas, United States

🇺🇸

Wellmonth Physician Services, Bristol, Virginia, United States

and more 170 locations

A Study on Spermatogenesis in Male Renal Transplant Recipients Receiving Valganciclovir (Valcyte®) Versus Untreated Matched Controls

Phase 4
Completed
Conditions
Cytomegalovirus Infections
Interventions
First Posted Date
2012-08-13
Last Posted Date
2018-08-31
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
59
Registration Number
NCT01663740
Locations
🇺🇸

Tufts Medical Center, Boston, Massachusetts, United States

🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

🇺🇸

University of California at San Francisco, San Francisco, California, United States

and more 16 locations

A Non-Interventional Study in Patients With Moderate to Severe Rheumatoid Arthritis Treated With RoActemra/Actemra (Tocilizumab)

Completed
Conditions
Rheumatoid Arthritis
First Posted Date
2012-08-13
Last Posted Date
2019-12-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
23
Registration Number
NCT01663506

A Study of Onartuzumab in Combination With mFOLFOX6 in Participants With Metastatic HER2-Negative and MET-Positive Gastroesophageal Cancer

Phase 3
Completed
Conditions
Gastric Cancer
Interventions
First Posted Date
2012-08-10
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
564
Registration Number
NCT01662869

An Observational Study of Avastin (Bevacizumab) in Combination With Paclitaxel in First-Line Treatment in Patients With HER2-Negative Metastatic Breast Cancer

Completed
Conditions
Breast Cancer
First Posted Date
2012-08-09
Last Posted Date
2017-08-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
16
Registration Number
NCT01661153
Locations
🇭🇷

Uni Hospital Split; Oncology & Radiotherapy, Split, Croatia

🇭🇷

General Hospital Varazdin, Varazdin, Croatia

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